≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
Mitochonic acid 5 Mitochonic acid 5 (MA-5) reduces mitochondrial apoptosis via upregulation of mitophagy . Mitochonic acid 5 regulates mitophagy via Bnip3 through the MAPK-ERK-Yap signaling pathway. Mitochonic acid 5 modulates mitochondrial ATP synthesis.
Targets
mitophagy ; Bnip3
| Pubchem Sid | 504772389 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504772389 |
| Sorrisi canonici | C1=CC=C2C(=C1)C(=CN2)C(CC(=O)C3=C(C=C(C=C3)F)F)C(=O)O |
| IUPAC Name | 4-(2,4-difluorophenyl)-2-(1H-indol-3-yl)-4-oxobutanoic acid |
| InChIKey | BOKQALWNGNLTOC-UHFFFAOYSA-N |
| INCHI | 1S/C18H13F2NO3/c19-10-5-6-12(15(20)7-10)17(22)8-13(18(23)24)14-9-21-16-4-2-1-3-11(14)16/h1-7,9,13,21H,8H2,(H,23,24) |
| Isomeri SMILES | C1=CC=C2C(=C1)C(=CN2)C(CC(=O)C3=C(C=C(C=C3)F)F)C(=O)O |
| Peso molecolare | 329.3 |
| Reaxy-Rn | 28882799 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=28882799&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Classe | Indoles and derivatives |
| Subclass | Indolyl carboxylic acids and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Indole-3-acetic acid derivatives |
| Alternative Parents | Alkyl-phenylketones Butyrophenones 3-alkylindoles Aryl alkyl ketones Benzoyl derivatives Gamma-keto acids and derivatives Fluorobenzenes Substituted pyrroles Aryl fluorides Vinylogous halides Heteroaromatic compounds Monocarboxylic acids and derivatives Azacyclic compounds Carboxylic acids Organonitrogen compounds Organofluorides Hydrocarbon derivatives Organic oxides |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Indole-3-acetic acid derivative - Alkyl-phenylketone - Butyrophenone - 3-alkylindole - Indole - Phenylketone - Aryl ketone - Aryl alkyl ketone - Gamma-keto acid - Benzoyl - Fluorobenzene - Halobenzene - Keto acid - Benzenoid - Monocyclic benzene moiety - Substituted pyrrole - Aryl fluoride - Aryl halide - Heteroaromatic compound - Vinylogous halide - Pyrrole - Ketone - Azacycle - Carboxylic acid - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Organofluoride - Organonitrogen compound - Organooxygen compound - Organic oxygen compound - Organic nitrogen compound - Carbonyl group - Hydrocarbon derivative - Organic oxide - Organohalogen compound - Aromatic heteropolycyclic compound |
| Descrizione | This compound belongs to the class of organic compounds known as indole-3-acetic acid derivatives. These are compounds containing an acetic acid (or a derivative) linked to the C3 carbon atom of an indole. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Data | Oggetto |
|---|---|---|---|
 G2208175 | Certificate of Analysis | Apr 03, 2025 | M412604 |
| G2208176 | Certificate of Analysis | Apr 03, 2025 | M412604 |
| G2208177 | Certificate of Analysis | Apr 03, 2025 | M412604 |
| G2208178 | Certificate of Analysis | Apr 03, 2025 | M412604 |
| G2208179 | Certificate of Analysis | Apr 03, 2025 | M412604 |
| L2420476 | Certificate of Analysis | Jun 04, 2022 | M412604 |
| Solubilità | Solubility (25°C) In vitro DMSO: 25 mg/mL (75.91 mM); Water: Insoluble; Ethanol: Insoluble; |
|---|---|
| Peso molecolare | 329.300 g/mol |
| XLogP3 | 3.100 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 5 |
| Exact Mass | 329.086 Da |
| Monoisotopic Mass | 329.086 Da |
| Topological Polar Surface Area | 70.200 Ų |
| Heavy Atom Count | 24 |
| Formal Charge | 0 |
| Complexity | 487.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
