MitoTEMPO hydrate - ≥95% , CAS No.1569257-94-8

CAS: 1569257-94-8 Cat. No.: M342668 Molecular Weight: 528.04

GRADE & PURITY ≥95%

Synonyms

Mito-TEMPO is known as a combination of TEMPO and triphenylphosphonium.

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Mito-TEMPO is a mitochondria-targeted antioxidant that helps protect against oxidative damage to the mitochondria. It has superoxide and alkyl radical scavenging properties. Mito-TEMPO has been shown to facilitate in the release of proapoptotic proteins from the mitochondria, attenuating ATP-depletion recovery-mediated necrosis and apoptosis. It has been shown to help block negative effects on the cardiac Na|+|channel in cardiomyocytes.

Specifications

Synonyms

Mito-TEMPO is known as a combination of TEMPO and triphenylphosphonium.

Specifications & Purity

≥95%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

MODULATOR

Note

Solutions in water, saline, ethanol or DMSO are stable at +4°C for 1-2 weeks. DMSO stock solution can be stored also at -20°C.

Purity

≥95%

Names and Identifiers

• Pubchem Sid: 504772336
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504772336
• Canonical Smiles: CC1(CC(CC(N1[O])(C)C)NC(=O)C[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)C.O.[Cl-]
• InChIKey: AIAJCDXYZBOVGT-UHFFFAOYSA-N
• INCHI: 1S/C29H34N2O2P.ClH.H2O/c1-28(2)20-23(21-29(3,4)31(28)33)30-27(32)22-34(24-14-8-5-9-15-24,25-16-10-6-11-17-25)26-18-12-7-13-19-26;;/h5-19,23H,20-22H2,1-4H3;1H;1H2
• Isomeric SMILES: CC1(CC(CC(N1[O])(C)C)NC(=O)C[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)C.O.[Cl-]
• Molecular Weight: 528.04
• Reaxy-Rn: 32173927
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=32173927&ln=

Chemical and Physical Properties

• Solubility: Soluble in water (10 mg/ml), methanol (15 mg/ml), 100% ethanol (15 mg/ml), and DMSO (10 mg/ml).