Myoseverin - ≥98% , CAS No.267402-71-1

CAS: 267402-71-1 Cat. No.: M135414 Formula: C₂₄H₂₈N₆O₂ Peso molecolare: 432.53

GRADE & PURITY ≥98%

Synonyms

NCGC00165829-01 | SCHEMBL13325947 | A12366 | myoseverin | J-016534 | MFCD02683596 | 9H-Purine-2,6-diamine, N,N'-bis((4-methoxyphenyl)methyl)-9-(1-methylethyl)- | SMP2_000092 | AS-56244 | AKOS027326433 | HMS2043N15 | 2-N,6-N-bis[(4-methoxyphenyl)methyl]-9-

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Panoramica

description：

Myoseverin is a microtuble-binding molecule and reversible inhibitor of tubulin polymerization. It binds to tublin leading to multinucleated myotubes fission. Myoseverin affects the expression of a variety of growth factor, immunomodulatory, extracellular matrix-remodeling, and stress response genes.

Specifications

Sinonimi

NCGC00165829-01 | SCHEMBL13325947 | A12366 | myoseverin | J-016534 | MFCD02683596 | 9H-Purine-2,6-diamine, N,N'-bis((4-methoxyphenyl)methyl)-9-(1-methylethyl)- | SMP2_000092 | AS-56244 | AKOS027326433 | HMS2043N15 | 2-N,6-N-bis[(4-methoxyphenyl)methyl]-9-

Specifiche e purezza

≥98%

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Purezza

≥98%

Nomi e identificatori

Pubchem Sid

504750764

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504750764

Sorrisi canonici

CC(C)N1C=NC2=C(N=C(N=C21)NCC3=CC=C(C=C3)OC)NCC4=CC=C(C=C4)OC

IUPAC Name

2-N,6-N-bis[(4-methoxyphenyl)methyl]-9-propan-2-ylpurine-2,6-diamine

InChIKey

IDCOTQWQVPRTNK-UHFFFAOYSA-N

INCHI

1S/C24H28N6O2/c1-16(2)30-15-27-21-22(25-13-17-5-9-19(31-3)10-6-17)28-24(29-23(21)30)26-14-18-7-11-20(32-4)12-8-18/h5-12,15-16H,13-14H2,1-4H3,(H2,25,26,28,29)

Isomeri SMILES

CC(C)N1C=NC2=C(N=C(N=C21)NCC3=CC=C(C=C3)OC)NCC4=CC=C(C=C4)OC

Peso molecolare

432.53

Reaxy-Rn

9086924

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=9086924&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Imidazopyrimidines
      • Subclass Purines and purine derivatives
        • Level5 6-aminopurines
          • Level6 6-alkylaminopurines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Imidazopyrimidines
• Subclass: Purines and purine derivatives
• Intermediate Tree Nodes: 6-aminopurines
• Direct Parent: 6-alkylaminopurines
• Alternative Parents: Phenoxy compounds Methoxybenzenes Benzylamines Anisoles Secondary alkylarylamines Aminopyrimidines and derivatives Alkyl aryl ethers N-substituted imidazoles Imidolactams Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: 6-alkylaminopurine - Phenoxy compound - Anisole - Benzylamine - Phenol ether - Methoxybenzene - Alkyl aryl ether - Aminopyrimidine - Secondary aliphatic/aromatic amine - Monocyclic benzene moiety - N-substituted imidazole - Pyrimidine - Imidolactam - Benzenoid - Heteroaromatic compound - Imidazole - Azole - Ether - Azacycle - Secondary amine - Organooxygen compound - Organonitrogen compound - Amine - Hydrocarbon derivative - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Aromatic heteropolycyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as 6-alkylaminopurines. These are compounds that contain an alkylamine group attached at the 6-position of a purine. Purine is a bicyclic aromatic compound made up of a pyrimidine ring fused to an imidazole ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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HCT-116 (91556 Activities)

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HepG2 (196354 Activities)

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HeLa (62764 Activities)

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APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)

Discover Target: APEX1

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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

Discover Target: TDP1

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RUNX1 Tbio Runt-related transcription factor 1/Core-binding factor subunit beta (7867 Activities)

Discover Target: RUNX1

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Obiettivi associati (non umani)

Rorc Nuclear receptor ROR-gamma (89407 Activities)

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FTL Ferritin light chain (43324 Activities)

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Meccanismi d'azione

Proprietà chimiche e fisiche

• Sensibilità: heat sensitive
• Punto di fusione (°C): 108 °C
• Peso molecolare: 432.500 g/mol
• XLogP3: 4.300
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 9
• Exact Mass: 432.227 Da
• Monoisotopic Mass: 432.227 Da
• Topological Polar Surface Area: 86.100 Ų
• Heavy Atom Count: 32
• Formal Charge: 0
• Complexity: 551.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Domande frequenti

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 267402-71-1, the molecular formula is C24H28N6O2, and the molecular weight is 432.53 g/mol. InChIKey IDCOTQWQVPRTNK-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.