N-Acetylprocainamide hydrochloride - ≥98%(HPLC) , CAS No.34118-92-8

CAS: 34118-92-8 Cat. No.: I169714 Formula: C₁₅H₂₄ClN₃O₂ Peso molecolare: 313.82 Numero EC: 251-831-2

QUALITÀ & PUREZZA ≥98%(HPLC)

Synonyms

Acecainide hydrochloride|Benzylpenicillin G|Benzamide, 4-(acetylamino)-N-(2-(diethylamino)ethyl)-, monohydrochloride|Riboazauratsil|2,3-Dihydro-3-hydroxy-1-methyl-1H-indole-5,6-dione|4'-((2-(Diethylamino)ethyl)carbamoyl)acetanilide monohydrochloride|Pharmakon1600-02300154|ASL 601|ASL 601(Acecainide)|(-)-Erythro-metaraminol|4-acetamido-N-(2-(diethylamino)ethyl)benzamide HCl|4-acetamido-N-[2-(diethylamino)ethyl]benzamide;hydrochloride|N-ACETYLPROCAINAMIDE HYDROCHLORIDE|ACECAINIDE HYDROCHLORIDE [MART.]|Opera_ID_64|Pilocar SMP|Acecainide HCl|Acecainide hydrochloride (USAN)|ASL601;Acecainide hydrochloride|4-acetamido-N-(2-(diethylamino)ethyl)benzamidehydrochloride|ACECAINIDE HYDROCHLORIDE [MI]|Acetamide, N-9H-fluoren-2-yl-|ASL-601|Acedainide; N-Acetylnovocainamide hydrochloride; NAPA|N-Acetylprocainamide (hydrochloride)|5-(trifluoromethyl)-1H-pyrimidine-2,4-dione|Camylofin free base|Acecainide hydrochloride [USAN]|NAPA

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifiche

Sinonimi

Acecainide hydrochloride | Benzylpenicillin G | Benzamide, 4-(acetylamino)-N-(2-(diethylamino)ethyl)-, monohydrochloride | Riboazauratsil | 2,3-Dihydro-3-hydroxy-1-methyl-1H-indole-5,6-dione | 4'-((2-(Diethylamino)ethyl)carbamoyl)acetanilide monohydrochloride | Pharmakon1600-02300154 | ASL 601 | ASL 601(Acecainide) | (-)-Erythro-metaramin Mostra altro

Specifiche e purezza

≥98%(HPLC)

Meccanismi biochimici e fisiologici

Class III antiarrhythmic. Increases the duration of the action potential by decreasing the delayed outward potassium current, slightly decreasing the calcium current, and slightly depressing the inward rectifier potassium current. This is the active metab

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Tipo di azione

INHIBITOR

Purezza

≥98%(HPLC)

Nomi e identificatori

Pubchem Sid

504754624

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504754624

Sorrisi canonici

CCN(CC)CCNC(=O)C1=CC=C(C=C1)NC(=O)C.Cl

IUPAC Name

4-acetamido-N-[2-(diethylamino)ethyl]benzamide;hydrochloride

InChIKey

IYEWBJUCJHKLHD-UHFFFAOYSA-N

INCHI

1S/C15H23N3O2.ClH/c1-4-18(5-2)11-10-16-15(20)13-6-8-14(9-7-13)17-12(3)19;/h6-9H,4-5,10-11H2,1-3H3,(H,16,20)(H,17,19);1H

Isomeri SMILES

CCN(CC)CCNC(=O)C1=CC=C(C=C1)NC(=O)C.Cl

WGK Germania

3

Peso molecolare

313.82

Reaxy-Rn

6548563

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=6548563&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Benzene and substituted derivatives
      • Subclass Benzoic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Benzene and substituted derivatives
• Subclass: Benzoic acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Acylaminobenzoic acid and derivatives
• Alternative Parents: Acetanilides N-acetylarylamines Benzamides Benzoyl derivatives Acetamides Trialkylamines Secondary carboxylic acid amides Amino acids and derivatives Organopnictogen compounds Organic oxides Hydrochlorides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Acylaminobenzoic acid or derivatives - Acetanilide - Benzamide - N-acetylarylamine - Anilide - Benzoyl - N-arylamide - Acetamide - Amino acid or derivatives - Carboxamide group - Tertiary aliphatic amine - Tertiary amine - Secondary carboxylic acid amide - Carboxylic acid derivative - Amine - Organooxygen compound - Organonitrogen compound - Hydrochloride - Hydrocarbon derivative - Carbonyl group - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Aromatic homomonocyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as acylaminobenzoic acid and derivatives. These are derivatives of amino benzoic acid derivatives where the amine group is N-acylated.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Obiettivi associati (umani)

KCNH2 Tclin HERG (29587 Activities)

Discover Target: KCNH2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)

Discover Target: THRB

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

POLB Tchem DNA polymerase beta (23632 Activities)

Discover Target: POLB

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

Discover Target: CYP3A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ATM Tchem Serine-protein kinase ATM (4198 Activities)

Discover Target: ATM

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)

Discover Target: EHMT2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SMN1 Tchem Survival motor neuron protein (34246 Activities)

Discover Target: SMN1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

BLM Tchem Bloom syndrome protein (4248 Activities)

Discover Target: BLM

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SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)

Discover Target: SLCO1B1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)

Discover Target: SLCO1B3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RUNX1 Tbio Runt-related transcription factor 1/Core-binding factor subunit beta (7867 Activities)

Discover Target: RUNX1

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Obiettivi associati (non umani)

Plasmodium falciparum (966862 Activities)

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Mus musculus (284745 Activities)

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GCN5 Histone acetyltransferase GCN5 (89 Activities)

Discover Target: GCN5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

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Meccanismi d'azione

Proprietà chimiche e fisiche

• Solubilità: H2O: 50 mg/mL
• Sensibilità: Moisture sensitive.
• Punto di fusione (°C): 184-186 °C
• Peso molecolare: 313.820 g/mol
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 7
• Exact Mass: 313.156 Da
• Monoisotopic Mass: 313.156 Da
• Topological Polar Surface Area: 61.400 Ų
• Heavy Atom Count: 21
• Formal Charge: 0
• Complexity: 308.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

Domande frequenti

What is the purity of this product, and how is it determined?

This product is supplied at ≥98% purity, determined by HPLC. Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 34118-92-8, the molecular formula is C15H24ClN3O2, and the molecular weight is 313.82 g/mol. InChIKey IYEWBJUCJHKLHD-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.