Naminidil - ≥99% , Sulfonylurea receptors; K-ATP channels opener, CAS No.220641-11-2, Sulfonylurea receptors; K-ATP channels opener

CAS: 220641-11-2 Cat. No.: N646738 Formula: C₁₅H₁₉N₅ Peso molecolare: 269.34 PubChem CID: 158438

GRADE & PURITY ≥99%

Synonyms

1-cyano-3-(4-cyanophenyl)-2-[(2R)-3,3-dimethylbutan-2-yl]guanidine | Naminidil | Naminidil [USAN:INN] | NAMINIDIL [USAN] | NAMINIDIL [INN] | AKOS040742268 | 7K50VT05OD | MS-23810 | Naminidil, (r)- | BMS-234303-01 | HY-100276 | Q27268440 | Guanidine, N-cya

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Panoramica

Naminidil is a cyanoguanidine K ATP opener.

In Vitro

Naminidil works through the potassium (K) channel. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:Potassium Channel

Specifications

Sinonimi

1-cyano-3-(4-cyanophenyl)-2-[(2R)-3,3-dimethylbutan-2-yl]guanidine | Naminidil | Naminidil [USAN:INN] | NAMINIDIL [USAN] | NAMINIDIL [INN] | AKOS040742268 | 7K50VT05OD | MS-23810 | Naminidil, (r)- | BMS-234303-01 | HY-100276 | Q27268440 | Guanidine, N-cya

Specifiche e purezza

≥99%

Meccanismi biochimici e fisiologici

Naminidil is a cyanoguanidine K ATP opener.

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Tipo di azione

OPENER

Meccanismo d'azione

Sulfonylurea receptors; K-ATP channels opener

Purezza

≥99%

Proprietà del prodotto

• ALogP: 3.5

Nomi e identificatori

• Pubchem Sid: 528766366
• Sorrisi canonici: CC(C(C)(C)C)N=C(NC#N)NC1=CC=C(C=C1)C#N
• IUPAC Name: 1-cyano-3-(4-cyanophenyl)-2-[(2R)-3,3-dimethylbutan-2-yl]guanidine
• InChIKey: PGYDRGZVXVVZQC-LLVKDONJSA-N
• INCHI: 1S/C15H19N5/c1-11(15(2,3)4)19-14(18-10-17)20-13-7-5-12(9-16)6-8-13/h5-8,11H,1-4H3,(H2,18,19,20)/t11-/m1/s1
• Isomeri SMILES: C[C@H](C(C)(C)C)N=C(NC#N)NC1=CC=C(C=C1)C#N
• CAS alternativo: 220641-11-2
• PubChem CID: 158438
• Peso molecolare: 269.34

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Benzene and substituted derivatives
      • Subclass Benzonitriles

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Benzene and substituted derivatives
• Subclass: Benzonitriles
• Intermediate Tree Nodes: Not available
• Direct Parent: Benzonitriles
• Alternative Parents: Guanidines Propargyl-type 1,3-dipolar organic compounds Nitriles Carboximidamides Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Benzonitrile - Guanidine - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Carboximidamide - Nitrile - Carbonitrile - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Aromatic homomonocyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as benzonitriles. These are organic compounds containing a benzene bearing a nitrile substituent.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Proprietà chimiche e fisiche

• Solubilità: DMSO : 125 mg/mL (464.10 mM; Need ultrasonic)
• Peso molecolare: 269.340 g/mol
• XLogP3: 3.500
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 269.164 Da
• Monoisotopic Mass: 269.164 Da
• Topological Polar Surface Area: 84.000 Ų
• Heavy Atom Count: 20
• Formal Charge: 0
• Complexity: 434.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1