≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Panoramica
Nampt activator-2 (compound 34) is a potent NAMPT activator, with EC 50 of 0.023 μM. Nampt activator-2 shows moderate activity against CYP2C9 (0.060 μM), 2D6 (0.41 μM) and 2C19 (0.59 μM).
In Vitro
Nampt activator-2 (compound 34) (10 μM, 4 h) results in a marked increase of both NMN and NAD in A549 lung epithelial cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
Nampt activator-2 (compound 34) (1 mg/kg iv and 10 mg/kg po, once) shows low plasma clearance, good exposure and excellent oral bioavailability (%F = 80) . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Mouse Dosage: 1 mg/kg iv and 10 mg/kg po Administration: IV, PO; once (Pharmacokinetic Analysis) Result: Pharmacokinetic Parameters of Nampt activator-2 in mouse . IV (1 mg/kg) PO (10 mg/kg) C max (ng/mL) 9550 AUC 0-24 (ng/mL∗h) 54463 t 1/2 (h) 3.2 CL (mL/min/kg) 3 Vd (L/kg) 0.61 F (%) 80
Form:Solid
Specifications
Specifiche e purezza
≥98%
Meccanismi biochimici e fisiologici
Nampt activator-2 (compound 34) is a potent NAMPT activator, with EC 50 of 0.023 μM. Nampt activator-2 shows moderate activity against CYP2C9 (0.060 μM), 2D6 (0.41 μM) and 2C19 (0.59 μM).
Condizioni di conservazione di stoccaggio
Store at -20°C
Spedito in
Ice chest + Ice pads
Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.
Tipo di azione
ACTIVATOR
Purezza
≥98%
Nomi e identificatori
Peso molecolare
390.84
Documentazione
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Certificati (CoA, COO, BSE/TSE e tabella di analisi)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Proprietà chimiche e fisiche
Solubilità
DMSO : 250 mg/mL (639.65 mM; Need ultrasonic)
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Recensioni
Recensioni dei clienti
Domande frequenti
What is the purity of this product?
This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 2237268-90-3, the molecular formula is C17H15ClN4O3S, and the molecular weight is 390.84 g/mol.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
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