NBI-98782 - 10mM in DMSO , CAS No.85081-18-1

CAS: 85081-18-1 Cat. No.: N654677 Formula: C₁₉H₂₉NO₃ Peso molecolare: 319.44 Numero EC: 809-846-2 PubChem CID: 14580381

QUALITÀ & PUREZZA 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

NBI-98782(alpha-dihydrotetrabenazine) is a vesicular monoamine transporter (VMAT2) inhibtior with an Ki value of 0.97 nM.IC50 value: 0.97± 0.48 nM Target: VMAT2The (+)-isomer showed high affinity in vitro (Ki = 0.97 +/- 0.48 nM) for the vesicular monoamine transporter (VMAT2) in rat brain striatum, whereas the (-)-isomer was inactive (Ki = 2.2 +/- 0.3 microM). Each isomer was then synthesized in carbon-11 labeled form, and regional brain biodistributions in mice determined after intravenous injection.

Specifiche

Specifiche e purezza

10mM in DMSO

Meccanismi biochimici e fisiologici

NBI-98782(alpha-dihydrotetrabenazine) is a vesicular monoamine transporter (VMAT2) inhibtior with an Ki value of 0.97 nM.\nIC50 value: 0.97± 0.48 nM \nTarget: VMAT2\n The (+)-isomer showed high affinity in vitro (Ki = 0.97 +/- 0.48 nM) for the vesicula

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Tipo di azione

INHIBITOR

Nomi e identificatori

Isomeri SMILES

CC(C)C[C@@H]1CN2CCC3=CC(=C(C=C3[C@H]2C[C@H]1O)OC)OC

PubChem CID

14580381

Peso molecolare

319.44