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ND-336 , CAS No.1807453-83-3
Disponibile su ordine
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Why this grade
for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Panoramica
ND-336 is a selective inhibitor of matrix metalloproteinase (MMP)-2 , MMP-9 , and MMP-14 , with K i s of 85, 150, and 120 nM, respectively. ND-336 accelerates diabetic wound healing in mice by lowering inflammation and by enhancing angiogenesis and re-epithelialization of the wound
In Vivo
ND-336 accelerates diabetic wound healing by decreasing inflammation and by enhancing angiogenesis and re-epithelialization of the wound, thus reversing the pathological condition . ND-336 (0.05-0.01 mg; topical application; daily for 14 day) accelerates diabetic wound healing . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Female diabetic db/db mice Dosage: 0.05, 0.025, and 0.01 mg Administration: Topical application; daily for 14 day Result: Healed 1.2- to 1.6-fold faster than those treated with ND-322 than those treated with vehicle.
Form:Solid
IC50& Target:MMP-2 85 nM (Ki) MMP-9 150 nM (Ki) MMP-14 120 nM (Ki)
Specifications
Meccanismi biochimici e fisiologici
ND-336 is a selective inhibitor of matrix metalloproteinase (MMP)-2 , MMP-9 , and MMP-14 , with K i s of 85, 150, and 120 nM, respectively. ND-336 accelerates diabetic wound healing in mice by lowering inflammation and by enhancing angiogenesis and re-epi
Condizioni di conservazione di stoccaggio
Store at -20°C
Spedito in
Ice chest + Ice pads
Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.
Tipo di azione
INHIBITOR
Nomi e identificatori
| Peso molecolare | 371.90 |
|---|
Documentazione
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificati (CoA, COO, BSE/TSE e tabella di analisi)
C of A & Other Certificates(BSE/TSE, COO):
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