NF-κB/MAPK-IN-1 - ≥98% , CAS No.2413940-56-2

CAS: 2413940-56-2 Cat. No.: N648054 Formula: C₂₇H₂₇NO₇ Peso molecolare: 477.51

GRADE & PURITY ≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Panoramica

NF-κB/MAPK-IN-1 (compound 11a) is a potent inhibitor of NF-κB and MAPK pathway. NF-κB/MAPK-IN-1 shows inhibitory activity against NO production, with an IC 50 of 6.96 µM. NF-κB/MAPK-IN-1 suppresses LPS-induced iNOS , COX-2 , ERΚ and P38 signaling activation. NF-κB/MAPK-IN-1 can prevent LPS induced inflammatory response in macrophages. NF-κB/MAPK-IN-1 can be used for rheumatoid arthritis (RA) research

Form:Solid

IC50& Target:NF-κB p38 COX-2

Specifications

Specifiche e purezza

≥98%

Meccanismi biochimici e fisiologici

NF-κB/MAPK-IN-1 (compound 11a) is a potent inhibitor of NF-κB and MAPK pathway. NF-κB/MAPK-IN-1 shows inhibitory activity against NO production, with an IC 50 of 6.96 µM. NF-κB/MAPK-IN-1 suppresses LPS-induced iNOS , COX-2 , ERΚ and P38 signaling activati

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Tipo di azione

INHIBITOR

Purezza

≥98%

Nomi e identificatori

Peso molecolare

477.51