Determine the necessary mass, volume, or concentration for preparing a solution.
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Moligand™, analytical standard Moligand™,Standard analitico for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Protected from light,Desiccated,Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 30 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
| ALogP | -0.5 |
|---|
| Pubchem Sid | 528770838 |
|---|---|
| Sorrisi canonici | C1C(=O)NC(=O)N1N=CC2=CC=C(O2)[N+](=O)[O-] |
| IUPAC Name | 1-[(E)-(5-nitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione |
| InChIKey | NXFQHRVNIOXGAQ-YCRREMRBSA-N |
| INCHI | 1S/C8H6N4O5/c13-6-4-11(8(14)10-6)9-3-5-1-2-7(17-5)12(15)16/h1-3H,4H2,(H,10,13,14)/b9-3+ |
| Isomeri SMILES | C1C(=O)NC(=O)N1/N=C/C2=CC=C(O2)[N+](=O)[O-] |
| WGK Germania | 3 |
| RTECS | MU2800000 |
| CAS alternativo | 54-87-5 |
| Peso molecolare | 238.16 |
| Beilstein | 893207 |
| Reaxy-Rn | 8132135 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8132135&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Classe | Azolidines |
| Subclass | Imidazolidines |
| Intermediate Tree Nodes | Imidazolidinones - Imidazolidinediones |
| Direct Parent | Hydantoins |
| Alternative Parents | Alpha amino acids and derivatives Nitroaromatic compounds Nitrofurans Semicarbazones Dicarboximides Heteroaromatic compounds Organic carbonic acids and derivatives Propargyl-type 1,3-dipolar organic compounds Organic oxoazanium compounds Oxacyclic compounds Azacyclic compounds Organic zwitterions Hydrocarbon derivatives Organopnictogen compounds Carbonyl compounds Organic oxides |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | Hydantoin - Alpha-amino acid or derivatives - Nitroaromatic compound - 2-nitrofuran - Semicarbazone - Dicarboximide - Furan - Heteroaromatic compound - Semicarbazide - C-nitro compound - Carbonic acid derivative - Organic nitro compound - Allyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Azacycle - Oxacycle - Propargyl-type 1,3-dipolar organic compound - Carboxylic acid derivative - Organic oxoazanium - Carbonyl group - Hydrocarbon derivative - Organic nitrogen compound - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organonitrogen compound - Organooxygen compound - Organic zwitterion - Aromatic heteromonocyclic compound |
| Descrizione | This compound belongs to the class of organic compounds known as hydantoins. These are heterocyclic compounds containing an imidazolidine substituted by ketone group at positions 2 and 4. |
| External Descriptors | organooxygen heterocyclic antibiotic - organonitrogen heterocyclic antibiotic - imidazolidine-2,4-dione - nitrofuran antibiotic |
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| Sensibilità | Light sensitive. |
|---|---|
| Punto di fusione (°C) | 270-272°C |
| Peso molecolare | 238.160 g/mol |
| XLogP3 | -0.500 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 2 |
| Exact Mass | 238.034 Da |
| Monoisotopic Mass | 238.034 Da |
| Topological Polar Surface Area | 121.000 Ų |
| Heavy Atom Count | 17 |
| Formal Charge | 0 |
| Complexity | 390.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 1 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 1 |
| Covalently-Bonded Unit Count | 1 |
| 1. Bao Siqi, Yu Xiaotong, Li Xiaolin. (2023) Study on the dominant mechanism of direct hole oxidation for the photodegradation of tetracycline. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, [PMID:38091223] [10.1007/s11356-023-31003-8] |
| 2. Ting Zhu, Jinyang Chen, Shasha Zeng, Jintao Chen, Chunjiao Qi. (2023) Highly Stable Fluorescent-Traffic-Light Sensor for Point-of-Care Detection of Tetracycline. ACS Sensors, [PMID:37862265] [10.1021/acssensors.3c01620] |
| 3. Yan Wu, Yue Zhou, Hongchen Long, Xiangyu Chen, Yuanyuan Jiang, Lei Zhang, Tao Le. (2023) A novel Zn/Eu-MOF for the highly sensitive, reversible and visualized sensing of ofloxacin residues in pork, beef and fish. FOOD CHEMISTRY, [PMID:37126953] [10.1016/j.foodchem.2023.136250] |
| 4. Yuyu Guo, Yiqing Chu, Xiaojuan Sun, Songhao Cao, Xin Li, Xinyue Li. (2023) Selective detection of nitrofurantoin by histidine-capped silver nanoclusters with blue luminescence. LUMINESCENCE, 38 (6): (796-802). [PMID:37078128] [10.1002/bio.4508] |
| 5. Mingyan Li, Taotao Zhe, Ruixia Li, Feier Bai, Pei Jia, Zhihao Xu, Xin Wang, Tong Bu, Haiyu Wu, Li Wang. (2023) ZIF-derived Co nanoparticles embedded into N-doped carbon nanotube composites for highly efficient electrochemical detection of nitrofurantoin in food. FOOD CHEMISTRY, [PMID:36944309] [10.1016/j.foodchem.2023.135948] |
| 6. Xu Wen, Xueling Yan, Xiaoling Zheng, Qiming Kou, Lulan Yang, Jiaming Tang, Xingyue Chen, Yong Xie, Tao Le. (2023) Selection and truncation of aptamers as fluorescence sensing platforms for selective and sensitive detection of nitrofurazone. ANALYTICA CHIMICA ACTA, [PMID:36935137] [10.1016/j.aca.2023.341044] |
| 7. Yuanjie Teng, Zhenni Wang, Shaohua Zuo, Xin Li, Yinxin Chen. (2022) Identification of antibiotic residues in aquatic products with surface-enhanced Raman scattering powered by 1-D convolutional neural networks. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:36549071] [10.1016/j.saa.2022.122195] |
| 8. Shuai Yan, Yongyu Li, Yankun Peng, Shaojin Ma, Donghai Han. (2022) Detection of nitrofurans residues in honey using surface-enhanced Raman spectroscopy. JOURNAL OF FOOD SCIENCE, 87 (7): (3318-3328). [PMID:35676764] [10.1111/1750-3841.16198] |
| 9. Liyin Bu, Xiaohui Chen, Qingyuan Song, Ding Jiang, Xueling Shan, Wenchang Wang, Zhidong Chen. (2022) Supersensitive detection of chloramphenicol with an EIS method based on molecularly imprinted polypyrrole at UiO-66 and CDs modified electrode. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2022.107459] |
| 10. Yu Wang, Jin-Yi Yang, Ying He, Lu Li, Jian-Xin Huang, Yuan-Xin Tian, Hong Wang, Zhen-Lin Xu, Yu-Dong Shen. (2021) Development of Time-Resolved Fluorescence Immunochromatographic Assays for Simultaneously Detecting Tylosin and Tilmicosin in Milk in Group-Screening Manner. Foods, 10 (8): (1838). [PMID:34441616] [10.3390/foods10081838] |
| 11. Qinchao Shao, De Zhang, Cai-e Wang, Zhexiang Tang, Mingqiang Zou, Xiaobing Yang, Huaping Gong, Zhi Yu, Shangzhong Jin, Pei Liang. (2021) Ag@MIL-101(Cr) Film Substrate with High SERS Enhancement Effect and Uniformity. Journal of Physical Chemistry C, [PMID:] [10.1021/acs.jpcc.1c01757] |
| 12. Zhifeng Cai, Shulin Pang, Liangliang Wu, Erxiao Hao, Jiaxin Rong. (2021) Highly sensitive and selective fluorescence sensing of nitrofurantoin based on water-soluble copper nanoclusters. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:33812238] [10.1016/j.saa.2021.119737] |
| 13. Huadong Zhang, Huasheng Lai, Xiangrong Wu, Gongke Li, Yufei Hu. (2020) CoFe2O4@HNTs/AuNPs Substrate for Rapid Magnetic Solid-Phase Extraction and Efficient SERS Detection of Complex Samples All-in-One. ANALYTICAL CHEMISTRY, [PMID:32069032] [10.1021/acs.analchem.0c00144] |
| 14. Yi Zhang, Zhongning Yu, Zhenfeng Yue, Jiamin Gao, Shaojing Wu, Zhuomin Zhang, Gongke Li. (2019) Rapid determination of trace nitrofurantoin in cosmetics by surface enhanced Raman spectroscopy using nanoarrayed hydroxyl polystyrene-based substrate. JOURNAL OF RAMAN SPECTROSCOPY, 50 (8): (1094-1102). [PMID:] [10.1002/jrs.5636] |
| 15. Li Zizhuo, Chen Yaodong, An Tingting, Liu Pengfei, Zhu Jiyuan, Yang Haichao, Zhang Wei, Dong Tianxiu, Jiang Jian, Zhang Yu, Jiang Maitao, Yang Xiuhua. (2019) RETRACTED ARTICLE: Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 38 (1): (1-15). [PMID:30922391] [10.1186/s13046-019-1134-y] |
| 16. Zixuan Zhou, Yuhan Jiang, Xin Luo, Ying Zhang, Lei Wang, Yaguang Sun, Mingchang Zhu, Shuangyan Wu. (2024) A novel coordination polymer array sensor for differential detection of nitroimidazole antibiotics. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2024.112405] |
| 17. Ruimin Lu, Yan Zhang, Daoping Zeng, Qihua Xu, Dan Wang, Peng Dai, Weijie Deng, Lin Kang, Xiaoxiao Ke, Luying Duan, Yanping Hong, Wuying Yang. (2024) Development of a monoclonal antibody-based indirect competitive chemiluminescence immunoassay for nitrofurantoin metabolite AHD residue in fish samples. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2024.112588] |
| 18. Hao-Jia Qin, Shuai Zhao, Hua-Ping Gong, Zhi Yu, Yufeng Wang, De Zhang, Pei Liang. (2024) Synthesis and characterization of Au@Ag/Ce-UIO-66 nanocomposite for highly sensitive detection of sulfadiazine residue. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2024.110415] |
| 19. Xinmei Qian, Chunxiang Li, Mingyu Zheng, Jinglun Wang, Haowen Huang, Keqin Deng. (2024) Bimetallic MOF derived electrocatalyst with magnetic alloy nanoparticles confined in S, N-doped carbon nanotubes: A disposable magnetic sensor for simultaneous determination of antibiotics in food. FOOD CHEMISTRY, [PMID:39581099] [10.1016/j.foodchem.2024.142141] |
| 20. Hui Li, Dongju Lin, Ying Peng, Jiang Zheng. (2017) Oxidative bioactivation of nitrofurantoin in rat liver microsomes. XENOBIOTICA, [PMID:27092978] [10.3109/00498254.2016.1164913] |
| 21. Mengru Liu, Taotao Zhe, Limin Zhu, Fan Li, Kaixuan Ma, Chenyu Xuan, Qinlin Feng, Shaohui Ouyang, Li Wang. (2025) Interfacial engineering of VS2/Ti3C2Tx MXene heterojunctions for portable electrochemical sensing of nitrofurantoin residues in food and water samples. FOOD CHEMISTRY, [PMID:40345038] [10.1016/j.foodchem.2025.144624] |
| 22. Tongtong Ma, Qiao Huang, Lei Yuan, Shugang Yan, Yalin Mo, Yibin Ying, Yingchun Fu, Jinming Pan. (2025) Tailored Fluorescent Metal–Organic Frameworks Hybrid Membrane Sensor Arrays: Simultaneous and Selective Quantification of Multiple Antibiotics. Advanced Science, [PMID:40285681] [10.1002/advs.202502452] |
| 23. Jiahang Song, Chuanhui Shi, Yijian Zhou, Shengqian Liang, Enzhou Liu, Chen Wang, Bing Wang, Bo Zhou, Chaoyang Wei, Zhuo Li. (2025) Synergistic effect of electron-rich alkyl-substituted subphthalocyanine H12SubPc-Oph-tBu and cobalt-doping for enhanced photocatalytic performance. Journal of Environmental Chemical Engineering, [PMID:] [10.1016/j.jece.2025.117231] |
| 24. Xinmei Qian, Chunxiang Li, Mingyu Zheng, Keqin Deng. (2025) A flower-like S, N-codoped carbon nanosheets with hybrid magnetic nanoparticles derived from MOFs for the construction of disposable nitrofurazone sensor. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2025.114239] |
| 25. Caizhen Zu, Xishun Peng, Yi Long, Man Peng, Cunwei Wang, Haili Zhang, Zhangwei Tan, Yuxue He, Zhongchen Bai. (2025) A SERS sensor of g-C3N4/Au@Ag thin film for detecting nitrofurantoin residues in honey. JOURNAL OF ALLOYS AND COMPOUNDS, [PMID:] [10.1016/j.jallcom.2025.184173] |
| 26. Youheng Pan, Tianyi Zhang, Yanyun Jin, Shixin Li, Jiandong Hu, Lanlan Li. (2025) Rapid and selective detection of furazolidone, chloramphenicol and dimetridazole using a multi-dimensional heterojunction electrochemical sensor. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2025.115807] |
| 27. Xinlan Wang, Menghan Qi, Zhengyi Chen, Gongke Li, Huasheng Lai. (2025) Rapid enrichment and determination of fishery drugs residue in fishes and shrimps by ZnO-Ag SERS substrate. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:41265107] [10.1016/j.saa.2025.127166] |
| 28. Zhang Haili, Peng Man, Lu Anjiang, Peng Xishun, Wang Cunwei, Zu Caizhen, Bai Zhongchen. (2026) A SERS sensor of Au/Ag nanoparticles grown on the surface of ZnO/PPy@PEDOT: PSS film for detecting norfloxacin residues in milk. MICROCHIMICA ACTA, 193 (2): (81). [PMID:41513929] [10.1007/s00604-025-07772-z] |
| 29. Xiaojing Mao, Huachang Li, Jiemin Liu, Jijun Liu, Pengcheng Han, Haijiao Xie. (2026) A fluorescein modified fluorescence sensor for simultaneous discrimination and detection of Fe3+ and nitrofurazone. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:41849902] [10.1016/j.saa.2026.127737] |
| 30. Yu Gan, Wenwen Lai, Mengbo Fan, Zhengchao Duan, Lianzhi Wang. (2026) Fabrication of a core-shell structured MOF@COF fluorescent composite and its sensing performance toward nitrofurantoin. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2026.119160] |
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