≥98% per flussi di lavoro cromatografici e analitici sensibili che richiedono un'interferenza minima della linea di base.
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Stoccaggio e spedizione
Store at 2-8°C Spedizione Wet ice. Consultare il COA specifico del lotto per le specifiche esatte.
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Documenti di qualità
SDS, COA, scheda tecnica e scheda delle specifiche disponibili per il download. COA specifico del lotto accessibile tramite ricerca per numero di lotto.
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Prova documentale
Citato in 1 pubblicazioni peer-reviewed su cromatografia, sintesi organica e reazioni di accoppiamento incrociato.
Panoramica
Notoginsenoside Ft1 is a saponin isolated from Panax notoginseng; stimulator of angiogenesis.IC50 value:Target: angiogenesis stimulatorin vitro: Ft1 increases translocalization of hypoxia-inducible factor-1α (HIF-1α) from cytoplasm to nuclei, where it binds to the vascular endothelial growth factor (VEGF) promoter, increasing the expression of VEGF mRNA and the subsequent secretion of the growth factor. Ft1 induces the activation of PI3K/AKT and Raf/MEK/ERK signaling pathways .Among the saponins examined, Ft1 was the most potent procoagulant and induced dose-dependent platelet aggregation. Ft1 reduced plasma coagulation indexes, decreased tail bleeding time and increased thrombogenesis. Moreover, it potentiated ADP-induced platelet aggregation and increased cytosolic Ca(2+) accumulation, effects that were attenuated by clopidogrel. Ft1 binds to platelet P2Y12 receptors. The increase in intracellular Ca(2+) evoked by Ft1 in HEK293 cells overexpressing P2Y12 receptors could be blocked by ticagrelor .Ft1 caused endothelium-dependent relaxations, which were abolished by l-NAME (inhibitor of nitric oxide synthases) and ODQ (inhibitor of soluble guanylyl cyclase). Ft1 increased the cGMP level in rat mesenteric arteries. GR and ER were present in the endothelial layer and their antagonism by RU486 and PHTPP, respectively, inhibited Ft1-induced endothelium-dependent relaxations and phosphorylations of eNOS , Akt and ERK1/2 .Ft1 showed the best inhibitory effect on cell proliferation of SH-SY5Y cells with IC50 of 45μM. Ft1 not only arrested the cell cycle at S, G2/M stages, but also promoted cell apoptosis . Ft1 up-regulated the protein expressions of cleaved caspase 3 , phospho-p53, p21, and cyclin B1, but down-regulated that of Bcl-2 . Moreover, Ft1 enhanced the phosphorylation of ERK1/2, JNK and p38 MAPK.in vivo: Ft1 promotes the formation of blood vessels in Matrigel plug and wound healing in mice.
Form:Solid
Specifiche
Specifiche e purezza
≥98%
Meccanismi biochimici e fisiologici
Notoginsenoside Ft1 is a saponin isolated from Panax notoginseng; stimulator of angiogenesis.\nIC50 value:\nTarget: angiogenesis stimulator\nin vitro: Ft1 increases translocalization of hypoxia-inducible factor-1α (HIF-1α) from cytoplasm to nuclei, where
Condizioni di conservazione di stoccaggio
Store at 2-8°C
Spedito in
Wet ice
Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.
This compound belongs to the class of organic compounds known as triterpene saponins. These are glycosylated derivatives of triterpene sapogenins. The sapogenin moiety backbone is usually based on the oleanane, ursane, taraxastane, bauerane, lanostane, lupeol, lupane, dammarane, cycloartane, friedelane, hopane, 9b,19-cyclo-lanostane, cycloartane, or cycloartanol skeleton.
External Descriptors
Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
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Recensioni
Recensioni dei clienti
Application Protocols
Item-specific (from Product Data)
No validated, product-specific application protocols are provided.
General guidance (not item-specific; for research use only)
Preparation of stock solutions:
Weigh the required amount quickly to limit moisture uptake.
Dissolve in anhydrous DMSO or methanol to prepare a concentrated stock (e.g., 10–50 mM, limited by solubility). Record the exact concentration gravimetrically or by quantitative NMR for standards work.
Filter through 0.22 µm (PTFE or PVDF) into amber vials. Store aliquots to avoid freeze–thaw.
Use in LC/LC–MS reference analyses:
Mobile phases: Water with 0.05–0.1% formic acid and acetonitrile or methanol.
Column: C18, sub-2–5 µm, 100–150 mm length; detect by ELSD/CAD or UV at ~203 nm; confirm by MS.
Prepare calibration curves across the expected range; verify linearity with the chosen detector.
In vitro assay preparation:
Dilute organic stock slowly into pre-equilibrated buffer with gentle mixing; aim for final DMSO ≤0.1–0.5% v/v.
Inspect for turbidity/precipitation; if present, reduce concentration or adjust cosolvent fraction cautiously.
Solid-phase storage and sampling:
Equilibrate vial to room temperature in a desiccator before opening to reduce condensation.
Note: Optimize all conditions for your specific assay/platform; no product-validated protocols are claimed for N646970.
Biological Roles
Item-specific (from Product Data)
No biological role information is specified for this item; it is supplied strictly for research use only.
General/literature context for dammarane-type notoginsenosides (not item-specific; no medical claims)
Origin and function in plants: Notoginsenosides are triterpenoid saponins from Panax notoginseng. In planta, saponins are considered secondary metabolites that may contribute to defense against herbivores and pathogens via membrane-disrupting surfactant properties.
Structural biology relevance: The dammarane scaffold (protopanaxadiol/triol derivatives) decorated with specific oligosaccharides confers amphipathic behavior, enabling interactions with lipid bilayers and sterols (e.g., cholesterol) and formation of non-covalent complexes.
Biophysical effects (in vitro): Saponins can alter membrane permeability, influence raft-like domain organization, and modulate uptake of co-administered molecules in cell systems. These effects are structure-dependent, sensitive to the number and position of sugar residues, and the hydroxylation pattern of the aglycone.
Metabolism (general): In mammalian systems, oral exposure to ginsenosides typically leads to deglycosylation by gut microbiota to smaller sapogenins that may have distinct physicochemical properties (literature observation). In purified in vitro systems, enzymatic or chemical hydrolysis yields defined metabolites useful for mechanistic studies.
Research utility
Notoginsenoside standards are widely used in phytochemical profiling, method development, and as positive controls to benchmark extraction and purification workflows, without implying any therapeutic effect.
Buffer Applications
Applicability
Notoginsenoside Ft1 is not a conventional buffering agent and does not establish defined pH ranges. Therefore, standard buffer recipes (phosphate, HEPES, Tris, etc.) are not directly applicable to this compound.
General handling in aqueous buffers (literature-informed, not item-specific)
Solubilization strategy: Prepare concentrated stocks in DMSO or methanol, then titrate into the desired aqueous buffer under gentle stirring to avoid local supersaturation and foaming. Final organic cosolvent is commonly kept ≤0.1–0.5% v/v for cell-based systems.
Surfactant considerations: Because saponins themselves are amphiphilic, avoid adding additional surfactants unless necessary; if required, use low levels of biocompatible surfactants (e.g., polysorbates) and verify no precipitation or mixed-micelle artifacts.
Ionic strength and pH: Mildly acidic to neutral pH (e.g., 6.0–7.4) often preserves glycosidic stability in short-term studies; strong acids/bases accelerate hydrolysis (general caution).
Filtration: Use low-protein-binding 0.22 µm filters to clarify solutions before quantitative assays.
If the goal is membrane permeabilization or uptake enhancement, consult primary literature for saponin-class agents; specific, validated buffer conditions for Notoginsenoside Ft1 are not established here and must be developed empirically for your system.
Green Alternatives
Applicability
As a target analyte/natural product, Notoginsenoside Ft1 itself is not replaced by a “greener” chemical. Green considerations primarily concern solvents and processes used for its handling, purification, and analysis.
Greener process choices (general; not item-specific)
Dissolution and assay:
Prefer ethanol/water mixtures over acetonitrile when compatible with detection and resolution.
For LC, explore water–ethanol gradients with volatile buffers as an alternative to acetonitrile; acknowledge potential tradeoffs (viscosity, backpressure, selectivity).
Extraction/purification:
Use aqueous ethanol or isopropanol for plant extraction instead of methylene chloride or 1,4-dioxane (literature best practices in natural products chemistry).
Solid-phase extraction (SPE) can minimize solvent volumes versus repeated liquid–liquid partitions.
Derivatizations:
Employ catalytic, solvent-free, or biocatalytic methods (e.g., lipase-mediated acylations) where feasible; reduce stoichiometric reagents and halogenated solvents.
Tradeoffs
Ethanol/water systems may increase run times and column pressures compared to acetonitrile; detector baselines can be less stable with high alcohol content.
Saponin amphiphilicity can cause foaming and challenging phase behavior; greener solvent choices must still ensure complete dissolution and reproducible analytics.
Documentation
Record solvent selection rationale and mass intensity (E-factor) for method validation packages to align with institutional green chemistry goals.
Pharmaceutical Uses
Scope and disclaimer
No pharmaceutical grade or compendial status is specified for this item; it is supplied for research use only. The following remarks discuss general formulation science of saponins and do not constitute clinical or therapeutic claims.
General/literature context (not item-specific)
Excipient/adjuvant research: Certain saponins (e.g., QS-21) have been investigated as vaccine adjuvants due to their amphiphilicity and membrane-interacting properties. While notoginsenosides are structurally related triterpenoid glycosides, each compound requires independent evaluation for safety and functionality.
Solubilization/absorption enhancement: Amphiphilic natural products are sometimes explored as permeability enhancers or stabilizers in experimental formulations; effects are highly structure- and concentration-dependent.
Analytical reference: Purified notoginsenosides serve as system suitability standards and reference markers in QC of botanical raw materials and extracts.
Development considerations
Stability: Glycosidic linkages are sensitive to hydrolysis; maintain appropriate pH and minimize thermal stress in liquid formulations.
Compatibility: Assess interactions with cholesterol-containing excipients (liposomes, lipid nanoparticles) as saponins can disrupt or rigidify bilayers.
Regulatory: Any intended pharmaceutical use requires comprehensive qualification (identity, purity, residual solvents, elemental impurities, microbial limits), none of which are specified for this catalog item.
Physical Properties
Item-specific (from Product Data)
Appearance: Not specified for this item; refer to CoA/Spec Sheet.
Molecular weight: Not specified for this item; refer to CoA/Spec Sheet.
Other specifications (bp, mp, density, solubility, logP, refractive index): Not specified for this item; refer to CoA/Spec Sheet.
General/literature expectations for dammarane-type saponins (not item-specific)
Physical state: Typically isolated as off-white to pale powders or amorphous solids; non-volatile; thermally labile.
Melting behavior: Many ginsenosides darken and decompose before a sharp melt; reported “mp” values are often decomposition ranges (literature observation).
Solubility: Amphiphilic. Often soluble in polar organics (methanol, ethanol, n-butanol, DMSO) and variably dispersible in water (may form micelles/colloids). Solubility in aprotic, less polar solvents (ethyl acetate, dichloromethane) is limited unless per-acetylated (literature trend).
pKa/logP: Conventional pKa/logP descriptors are of limited use due to multiple neutral hydroxyls and high hydrophilicity from sugar units; apparent partitioning is strongly system- and aggregation-dependent (literature note).
UV/Vis: Weak absorbance above 210–220 nm; analytical detection commonly by ELSD, CAD, MS, or after derivatization; HPLC-UV at 203–205 nm is frequently employed (literature practice).
Stability: Moisture and heat can promote hydrolysis of glycosidic bonds; prolonged exposure to strong acid/base causes degradation (literature cautions).
Analytical handling tips (general)
Prepare stock solutions in dry DMSO or methanol for reference-standard work; filter (0.22 µm) to remove particulates prior to LC.
For quantitative work, minimize freeze–thaw cycles and use amber vials to limit photolysis at low UV.
Quality and Grades
Item-specific (from Product Data)
Grade/Purity: Not specified for this item; refer to CoA/Spec Sheet.
Interpretation and guidance
Without a stated grade (e.g., analytical standard, ≥95%, HPLC grade), end-users should consult the Certificate of Analysis (CoA) for:
Assay methodology and value (e.g., HPLC area %, quantitative NMR).
Identity confirmation (HRMS/ESI, 1H/13C NMR, IR).
Residual solvents and water content.
Related substances profile and limits.
Natural product saponins often present isomeric/positional impurities or co-eluting congeners. Ensure the specified assay and chromatographic system match your analytical method if you require trace-impurity control.
Stabilizers: None stated for this item. If present in a lot, stabilizers or counterions will be declared on the CoA; evaluate any impact on downstream bioassays or derivatizations.
Reference-standard use: For quantitative LC, verify response factor consistency across detectors (UV at ~203 nm vs ELSD/CAD) and confirm mass balance (assay + moisture + residual solvents ~100%).
Batch-to-batch variation: Plant-derived compounds can exhibit minor variability in impurity patterns. Where method transfer robustness is critical, secure sufficient material from a single lot.
Documentation
In absence of catalog grade declarations, rely on: CoA, Spec Sheet, and SDS for item-specific quality information.
If regulatory or pharmacopoeial compliance is required, confirm explicitly; none is stated for this catalog entry.
Reaction and Applications
Item-specific (from Product Data)
Category: Small molecules and compound libraries (小分子和化合物库).
Manufacturer Applications: Not provided beyond categorization.
General/literature applications for dammarane-type saponins (not item-specific)
Chemical biology probes: Saponins interact with membrane sterols (e.g., cholesterol) and can modulate membrane permeability and microdomain organization. Researchers exploit these properties in mechanistic studies of membrane dynamics and endocytosis.
Reference standards: Employed in metabolomics, phytochemical profiling, and QC of Panax spp. extracts via HPLC/UPLC–MS, ELSD, or CAD.
Structure–activity relationship (SAR) studies: Systematic modification of sugar moieties (deglycosylation/reglycosylation) or aglycone hydroxylation/oxidation patterns to map bioactivity trends across ginsenoside families.
Semi-synthesis: Per-acetylation, selective acylation/alkylation, sulfation/phosphorylation of hydroxyl groups to alter solubility, stability, or membrane affinity.
Formulation science: As model amphiphiles to study micellization, vesicle disruption, or adjuvant-like behaviors in vitro.
Practical notes
Maintain anhydrous conditions for protection/functionalization steps; many reactions proceed cleaner on fully or partially protected glycosides.
Monitor reactions by LC–MS rather than UV-only due to weak chromophores; derivatize for TLC visualization (e.g., anisaldehyde–sulfuric acid, vanillin–H2SO4 sprays).
Enzymatic transformations (glycosidases, glycosyltransferases, P450s) offer regioselectivity unattainable by purely chemical routes, albeit with narrower substrate scopes.
Reaction Conditions
Item-specific (from Product Data)
No reaction condition specifications are provided for this item.
General/literature guidance for common transformations of triterpenoid saponins (not item-specific)
Per-acetylation: Ac2O (5–10 equiv per OH), catalytic DMAP, pyridine or DCM/pyridine, 0 °C to rt, 2–24 h. Workup with saturated NaHCO3; purification by silica gel (derivatization improves normal-phase behavior).
Selective acylation: Steglich conditions (DCC or EDCI, DMAP) in DCM/DMF, 0 °C to rt. Protect competing hydroxyls to achieve regioselectivity.
Silyl protection: TBDMS-Cl/imidazole in DMF, rt to 40 °C; remove with TBAF in THF at 0–25 °C.
Oxidation (mild): TEMPO/NaOCl/NaBr in biphasic CH2Cl2/H2O, pH ~9–10, 0–5 °C for primary alcohols; or Dess–Martin periodinane in DCM for secondary alcohols. Carefully control equivalents to avoid over-oxidation.
Acidic hydrolysis of glycosides: Dilute mineral acid (e.g., 0.05–0.5 M HCl or H2SO4) in aqueous MeOH/H2O, 40–80 °C, minutes to hours; monitor closely by LC–MS to prevent aglycone degradation.
Enzymatic transformations: Glycosidases (β-glucosidase, α-L-rhamnosidase) in buffered aqueous media (pH 5–6, 25–40 °C) offer selectivity with minimal side reactions; times range from hours to days depending on substrate accessibility.
Analytical controls
Use MS-compatible solvents and volatile buffers when possible; for workups, avoid high pH/temperature that can cleave glycosidic bonds.
Due to weak UV chromophores, rely on ELSD/CAD or MS for kinetic monitoring; for TLC, use anisaldehyde/vanillin stains.
Yields
Reported yields in literature for selective modifications vary widely (30–90%) depending on substitution pattern and protection strategy; optimize conditions per substrate.
Safety and Handling
Item-specific (from Product Data)
GHS classification, signal word, pictograms, and H-statements: Not specified for this item; refer to SDS.
Storage conditions: Store at 2–8 °C.
Shipped on: Wet ice.
General safety guidance for triterpenoid saponins (not item-specific; consult SDS for authoritative instructions)
Hazards: Saponins can be irritant and are known to disrupt biological membranes due to their surfactant-like behavior. Avoid inhalation of dust and contact with eyes/skin.
PPE: Laboratory coat, safety glasses/goggles, and appropriate chemical-resistant gloves (e.g., nitrile). Use in a fume hood or well-ventilated area to avoid aerosolization of powders/solutions.
Handling: Avoid generating dust; dissolve gently with stirring to prevent foaming. Use dedicated spatulas and antistatic measures for microgram–milligram manipulations.
Incompatibilities: Strong acids/bases (promote glycosidic hydrolysis), strong oxidizers, and elevated temperatures. Avoid prolonged exposure to moisture.
First aid (general):
Skin/eye contact: Rinse with copious water for ≥15 minutes; remove contaminated clothing; seek medical attention if irritation persists.
Inhalation: Move to fresh air; seek medical attention if symptoms appear.
Ingestion: Rinse mouth; do not induce vomiting; seek medical advice.
Spills: Avoid dry sweeping; lightly moisten and wipe, or use HEPA-filter vacuum suitable for fine powders. Dispose according to institutional and local regulations.
Fire: Not expected to be highly flammable as a solid; use CO2, dry chemical, or water spray as appropriate. Thermal decomposition may produce CO/CO2 and irritant fumes.
Always defer to the current SDS for N646970 for definitive hazard classification and response measures.
Solvent Selection
Applicability: Notoginsenoside Ft1 is a polar, amphiphilic, high-MW triterpenoid saponin. Solvent choice primarily affects solubility, aggregation, and chromatographic behavior.
Item-specific (from Product Data)
No solvent specifications provided. Storage at 2–8 °C; shipped on wet ice.
General/literature guidance (not item-specific)
Stock solutions: DMSO and methanol are frequent choices for reference standards due to miscibility with aqueous mobile phases and bioassay buffers. Ethanol can work but may require higher volumes.
Aqueous media: Saponins may self-assemble; water solubility is system-dependent. Dilution of DMSO stocks into buffered saline can yield clear solutions at low concentrations; addition order and slow mixing help prevent precipitation/foaming.
Miscibility profile: Insoluble/poorly soluble in nonpolar solvents (hexanes, toluene). Limited solubility in medium polarity solvents (EtOAc, MTBE) unless derivatized.
Chromatography solvents: For analytical/preparative LC, typical eluents are water–acetonitrile or water–methanol with low % acid (e.g., 0.05–0.1% formic acid) to sharpen peaks and aid MS ionization.
Dielectric/polarity considerations: High dielectric solvents (DMSO ε ~47, methanol ε ~33 at 20 °C; literature) favor dissolution of polyhydroxylated glycosides; hydrogen-bond donor/acceptor capability is beneficial.
Practical tips
Warm gently (≤40 °C) and sonicate to assist dissolution; avoid prolonged heating.
Filter solutions (0.22 µm PTFE or PVDF) before quantitative analysis.
Minimize final DMSO content in biological systems (commonly ≤0.1–0.5% v/v) to avoid confounding effects.
Storage and Reconstitution
Item-specific (from Product Data)
Storage conditions: Store at 2–8 °C.
Shipping: Wet ice.
Appearance: Not specified for this item; refer to CoA/Spec Sheet.
General handling & stability guidance (not item-specific)
Protection: Keep tightly closed in a dry, inert atmosphere. Use desiccants and, if available, nitrogen/argon backfill after opening. Protect from light (amber vials) to minimize low-UV photodegradation.
Shelf life: Natural product saponins are generally stable as dry solids when cool and dry; avoid repeated temperature cycling and humidity exposure. Review the CoA for any lot-specific retest/expiry date.
Reconstitution:
Solvents: DMSO or methanol recommended for initial dissolution; ethanol is an alternative. Warm gently (≤40 °C) and sonicate if needed. Avoid strong acids/bases during dissolution.
Working solutions: For aqueous applications, dilute organic stocks into buffer with gentle stirring to minimize foaming. Prepare fresh as needed; many saponin solutions show time-dependent aggregation or hydrolysis.
Aliquoting and storage of solutions:
Prepare single-use aliquots to avoid freeze–thaw; store DMSO stocks at −20 °C or below, methanolic stocks at −20 °C when feasible, protected from light. Verify stability by LC before critical experiments.
Disposal
Dispose of unused material and solutions according to institutional guidelines for organic chemicals and natural products. Do not discharge to drains without appropriate treatment.
Structure and Identity
Brief overview
Item-specific (from Product Data):
Product name: Notoginsenoside Ft1 (SKU: N646970)
CAS: 155683-00-4
InChIKey: 203079 (as provided)
SMILES: Not specified for this item; refer to CoA/Spec Sheet.
Molecular formula: Not specified for this item; refer to CoA/Spec Sheet.
Molecular weight: Not specified for this item; refer to CoA/Spec Sheet.
Notoginsenoside Ft1 is a dammarane-type triterpenoid saponin isolated from Panax notoginseng. Compounds in this class feature a tetracyclic dammarane aglycone (protopanaxadiol or protopanaxatriol core) covalently linked to one or more sugar residues (often glucose, rhamnose, arabinose) via O-glycosidic bonds at C-3 and/or C-20.
Functional groups expected for dammarane saponins include: multiple secondary/tertiary hydroxyls on the steroid-like core, acetal linkages within glycoside(s), and numerous alcohol functions on the saccharide units. No classical chromophore is present; UV detection often relies on low-wavelength monitoring or derivatization.
2D structural features (literature, class-level): A fused 4-ring carbon skeleton (trans-decalin fused to additional rings) bearing hydroxyl substituents; one or more oligosaccharide chains attached through glycosidic oxygen(s). Stereochemistry across the ring junctions is well-defined and typically all-trans for the dammarane framework; multiple chiral centers exist both on the aglycone and sugars.
Note: Exact stereochemistry, substitution pattern, and sugar composition for Ft1 should be confirmed from the Certificate of Analysis or primary literature for this specific lot.
Synthetic Utility
Position in synthesis
Notoginsenoside Ft1 is a complex, polyhydroxylated triterpenoid glycoside. While not commonly used as a building block in stepwise synthesis, it is a versatile substrate for derivatization, semi-synthesis, and enzymatic modification studies.
Transformations (general literature, not item-specific)
Protection–deprotection: Global per-acetylation (Ac2O/pyridine or Ac2O/DMAP) to improve solubility in apolar media; selective protection of primary vs secondary hydroxyls can be achieved with silyl groups (e.g., TBDMS/TBDPS) under carefully tuned conditions.
Esterification/Carbonate formation: Installation of acyl or carbonate groups at specific hydroxyls to modulate lipophilicity and membrane affinity.
Oxidation/reduction on aglycone: TEMPO-mediated oxidation or Jones-type conditions (harsh) can functionalize secondary alcohols; milder catalytic oxidations preferred to preserve glycosides. Hydrogenation of double bonds (if present) under Pd/C.
Glycosidic editing: Partial acid hydrolysis (aqueous AcOH or TFA, controlled) to afford lower-order glycosides; enzymatic deglycosylation/reglycosylation with glycosidases and glycosyltransferases for regioselective remodeling.
Sulfation/phosphorylation: Install ionic groups (SO3−, PO3−) to increase aqueous solubility for biophysical studies.
Analytical and purification notes
Monitor by LC–MS and evaporative detectors; TLC visualization with anisaldehyde–H2SO4 or vanillin stains is effective.
Purify using reversed-phase chromatography (C18) with water–MeOH/ACN gradients; normal-phase often requires derivatization due to strong polarity.
Caveats
Extended exposure to strong acids/bases leads to decomposition. Use buffered, mild conditions and low temperatures to maintain integrity.
Target Specificity
Applicability
This section is typically relevant to biologics such as antibodies, enzymes, or targeted probes. Notoginsenoside Ft1 is a small-molecule natural product. No antigen/epitope specificity, clone, isotype, or species reactivity applies.
Item-specific (from Product Data)
No target specificity information is provided or expected for this compound.
Guidance
If using Ft1 as a biochemical probe, define target engagement empirically (e.g., membrane models, cholesterol binding assays) and report assay conditions explicitly, as no canonical “target” is established here.
Domande frequenti
What is the purity of this product?
This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
How should this product be stored?
Store at 2–8 °C. Refrigerated storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 155683-00-4, the molecular formula is C47H80O17, and the molecular weight is 917.13 g/mol. InChIKey LLXVPTXOKTYXHU-UGGLCNOCSA-N.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
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