OH-PEG4-Tos(Tos-PEG4) - ≥98% , CAS No.77544-60-6

CAS: 77544-60-6 Cat. No.: P595688 Formula: C₁₅H₂₄O₇S Peso molecolare: 348.41 Numero EC: 804-383-2

GRADE & PURITY ≥98%

Synonyms

SY108295 | BS-42630 | tetraethylene glycol tosylate | 2-[2-[2-(2-HYDROXYETHOXY)ETHOXY]ETHOXY]-1-(P-TOLUENESULFONYL)-ETHANOL | Ethanol, 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-,1-(4-methylbenzenesulfonate) | 10.14272/FGDJUEZBMFELRW-UHFFFAOYSA-N | 2-[2-[2-(

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Panoramica

Refractive index: n20/d 1.507

OH-PEG4-Tos(Tos-PEG4) is a cleavable and acylhydrazone-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Tetraethylene glycol monotosylate also can be used as a PROTAC linker that can be used in the synthesis of PROTACs.

Specifications

Sinonimi

SY108295 | BS-42630 | tetraethylene glycol tosylate | 2-[2-[2-(2-HYDROXYETHOXY)ETHOXY]ETHOXY]-1-(P-TOLUENESULFONYL)-ETHANOL | Ethanol, 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-,1-(4-methylbenzenesulfonate) | 10.14272/FGDJUEZBMFELRW-UHFFFAOYSA-N | 2-[2-[2-(

Specifiche e purezza

≥98%

Condizioni di conservazione di stoccaggio

Store at 2-8°C,Argon charged

Spedito in

Wet ice

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Purezza

≥98%

Nomi e identificatori

Pubchem Sid

528766472

Sorrisi canonici

CC1=CC=C(C=C1)S(=O)(=O)OCCOCCOCCOCCO

IUPAC Name

2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate

InChIKey

FGDJUEZBMFELRW-UHFFFAOYSA-N

INCHI

1S/C15H24O7S/c1-14-2-4-15(5-3-14)23(17,18)22-13-12-21-11-10-20-9-8-19-7-6-16/h2-5,16H,6-13H2,1H3

Isomeri SMILES

CC1=CC=C(C=C1)S(=O)(=O)OCCOCCOCCOCCO

Peso molecolare

348.41

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Benzene and substituted derivatives
      • Subclass Benzenesulfonic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Benzene and substituted derivatives
• Subclass: Benzenesulfonic acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Benzenesulfonate esters
• Alternative Parents: p-Methylbenzenesulfonates Tosyl compounds Polyethylene glycols Benzenesulfonyl compounds Arylsulfonic acids and derivatives Organosulfonic acid esters Sulfonyls Primary alcohols Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Benzenesulfonate ester - P-methylbenzenesulfonate - Tosyl compound - Polyethylene glycol - Arylsulfonic acid or derivatives - Benzenesulfonyl group - Toluene - Organosulfonic acid ester - Sulfonyl - Organosulfonic acid or derivatives - Organic sulfonic acid or derivatives - Ether - Dialkyl ether - Organic oxide - Alcohol - Primary alcohol - Organosulfur compound - Organooxygen compound - Organic oxygen compound - Hydrocarbon derivative - Aromatic homomonocyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as benzenesulfonate esters. These are arenesulfonate esters that result from the formal condensation of the hydroxy group of an alcohol, enol, phenol or heteroarenol with benzenesulfonic acid.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Proprietà chimiche e fisiche

• Solubilità: Solubility in Water, DMSO, DCM, DMF
• Punto di infiammabilità (°C): > 110 °C
• Peso molecolare: 348.400 g/mol
• XLogP3: 0.300
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 13
• Exact Mass: 348.124 Da
• Monoisotopic Mass: 348.124 Da
• Topological Polar Surface Area: 99.700 Ų
• Heavy Atom Count: 23
• Formal Charge: 0
• Complexity: 372.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1