OTS186935 hydrochloride - 10mM in DMSO , CAS No.O661587(DMSO)

CAS: O661587(DMSO) Cat. No.: O661587 Formula: C₂₅H₂₆ClN₅O₂.8/5HCl Peso molecolare: 522.31

GRADE & PURITY 10mM in DMSO

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

OTS186935 hydrochloride is a potent protein methyltransferase SUV39H2 inhibitor with an IC 50 of 6.49 nM. OTS186935 hydrochloride shows significant inhibition of tumor growth in mouse xenograft models without any detectable toxicity. OTS193320 hydrochlori

IC50& Target:IC50: 6.49 nM (SUV39H2)

In Vitro:OTS186935 hydrochloride inhibits A549 cell growth with an IC 50 of 0.67 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo:OTS186935 hydrochloride (10mg/kg or 25mg/kg; intravenously; once daily for 14 days) exhibits growth suppressive effects in human cancer cell line derived xenograft models. MCE has not independently confirmed the accuracy of these methods. They are

Biological Activity:OTS186935 hydrochloride is a potent protein methyltransferase SUV39H2 inhibitor with an IC 50 of 6.49 nM. OTS186935 hydrochloride shows significant inhibition of tumor growth in mouse xenograft models without any detectable toxicity. OTS193320 hydrochlori

Specifications

Specifiche e purezza

10mM in DMSO

Condizioni di conservazione di stoccaggio

Desiccated,Store at -80°C

Spedito in

Dry ice packs + Cold packs

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Tipo di azione

INHIBITOR

Nomi e identificatori

Peso molecolare

522.31