Oxybutynin hydrochloride - 10mM in DMSO , Muscarinic acetylcholine receptor M2 antagonist, CAS No.1508-65-2, Muscarinic acetylcholine receptor M2 antagonist

CAS: 1508-65-2 Cat. No.: O409141 Formula: C₂₂H₃₁NO₃·HCl Peso molecolare: 393.95 Numero EC: 216-139-7

GRADE & PURITY 10mM in DMSO

Synonyms

Benzeneacetic acid, α-cyclohexyl-α-hydroxy-, 4-(diethylamino)-2-butyn-1-yl ester, hydrochloride (1:1)

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

Information

Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.
In vitro

Oxybutynin relieves urinary and bladder difficulties, including frequent urination and inability to control urination (urge incontinence), by decreasing muscle spasms of the bladder. Oxybutynin competitively antagonizes the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor. Oxybutynin also has direct spasmolytic effects on bladder smooth muscle as a calcium antagonist and local anesthetic, but at concentrations far above those used clinically.

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥97%

Specifications

Sinonimi

Benzeneacetic acid, α-cyclohexyl-α-hydroxy-, 4-(diethylamino)-2-butyn-1-yl ester, hydrochloride (1:1)

Specifiche e purezza

10mM in DMSO

Meccanismi biochimici e fisiologici

Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

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Tipo di azione

ANTAGONIST

Meccanismo d'azione

Muscarinic acetylcholine receptor M2 antagonist

Nomi e identificatori

• Isomeri SMILES: CCN(CC)CC#CCOC(=O)C(C1CCCCC1)(C2=CC=CC=C2)O.Cl
• WGK Germania: 3
• RTECS: GV2800000
• Peso molecolare: 393.95
• Reaxy-Rn: 4833152
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4833152&ln=

Proprietà chimiche e fisiche

• Solubilità: Solubility (25°C) In vitro Ethanol: 60 mg/mL (200.34 mM); DMSO: 19 mg/mL (63.44 mM); Water: Insoluble

Riferimenti

1. Chen Wang, Dongyang Zhu, Jian Zhang, Yingxiang Du.  (2022)  Homochiral iron-based γ-cyclodextrin metal-organic framework for stereoisomer separation in the open tubular capillary electrochromatography.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,      [PMID:35462287] [10.1016/j.jpba.2022.114777]