Oxytetracycline - Moligand™, ≥98% , CAS No.79-57-2

CAS: 79-57-2 Cat. No.: O304654 Formula: C₂₂H₂₄N₂O₉ Peso molecolare: 460.43 Numero EC: 201-212-8

GRADE & PURITY Moligand™, ≥98%

Synonyms

Oxyterracine | Terramycin | Terrafungine | Oxitetracyclin | oxytetracycline | Biostat | Oxitetraciclina | Oxymycin | Oxytetracycline anhydrous | Adamycin | Oxytetracyclinum | Oxytetracycline (anhydrous) | Ryomycin | Geomycin | Oxyterracin | Oxytetracyclin

Storage

Store at 2-8°C,Protected from light

Shipped In

Wet ice

Panoramica

Oxytetracycline is an anti-inflammatory, antibiotic, and anti-proliferative agent shown to inhibit mitochondrial protein synthesis. Mechanistic studies show that this compound reduces cytochrome c activity which eventually causes cell growth arrest. Additionally, Oxytetracycline has demonstrated the ability to reduce murine bronchial inflammation. The anti-inflammatory characteristics of this agent are due to its ability to cause a decrease in IL-4, IL-5, IL-13, immune cells, and the ovalbumin-specific IgE. Data suggests that Oxytetracycline is also an inhibitor of NF-κB activation via phosphorylation and degradation of IκB-α.

Specifications

Sinonimi

Oxyterracine | Terramycin | Terrafungine | Oxitetracyclin | oxytetracycline | Biostat | Oxitetraciclina | Oxymycin | Oxytetracycline anhydrous | Adamycin | Oxytetracyclinum | Oxytetracycline (anhydrous) | Ryomycin | Geomycin | Oxyterracin | Oxytetracyclin

Specifiche e purezza

Moligand™, ≥98%

Meccanismi biochimici e fisiologici

Tetracycline antibiotic. Inhibits mitochondrial protein synthesis. Anti-inflammatory effects in vivo.

Condizioni di conservazione di stoccaggio

Store at 2-8°C,Protected from light

Spedito in

Wet ice

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Grado

Moligand™

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purezza

≥98%

Nomi e identificatori

Pubchem Sid

508813147

Sorrisi canonici

CC1(C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O

IUPAC Name

(4S,4aR,5S,5aR,6S,12aR)-4-(dimethylamino)-1,5,6,10,11,12a-hexahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide

InChIKey

OWFJMIVZYSDULZ-PXOLEDIWSA-N

INCHI

1S/C22H24N2O9/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29/h4-6,12-14,17,25-26,28,30,32-33H,1-3H3,(H2,23,31)/t12-,13-,14+,17+,21-,22+/m1/s1

Isomeri SMILES

C[C@@]1([C@H]2[C@@H]([C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O

Peso molecolare

460.43

Reaxy-Rn

33487456

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=33487456&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Phenylpropanoids and polyketides
    • Classe Tetracyclines

• Kingdom: Organic compounds
• Superclass: Phenylpropanoids and polyketides
• Classe: Tetracyclines
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Tetracyclines
• Alternative Parents: Naphthols and derivatives 1-hydroxy-2-unsubstituted benzenoids 1-hydroxy-4-unsubstituted benzenoids Aralkylamines Cyclohexenones Vinylogous acids Tertiary alcohols Trialkylamines Secondary alcohols Cyclic alcohols and derivatives Polyols Carboximidic acids Enols Organopnictogen compounds Hydrocarbon derivatives Organic oxides
• Molecular Framework: Aromatic homopolycyclic compounds
• Substituents: Tetracycline - 1-naphthol - Naphthalene - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Cyclohexenone - Aralkylamine - Benzenoid - Cyclic alcohol - Tertiary alcohol - Vinylogous acid - Cyclic ketone - Tertiary aliphatic amine - Tertiary amine - Secondary alcohol - Ketone - Carboximidic acid - Carboximidic acid derivative - Polyol - Enol - Hydrocarbon derivative - Organic oxygen compound - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Alcohol - Amine - Organopnictogen compound - Carbonyl group - Organic oxide - Aromatic homopolycyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as tetracyclines. These are polyketides having an octahydrotetracene-2-carboxamide skeleton, substituted with many hydroxy and other groups.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Proprietà chimiche e fisiche

• Solubilità: Sparingly soluble in aqueous solution at 0.6 mg/mL
• Sensibilità: Air sensitive;Light sensitive;Moisture sensitive
• Punto di fusione (°C): 183 °C
• Peso molecolare: 460.400 g/mol
• XLogP3: -1.600
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 2
• Exact Mass: 460.148 Da
• Monoisotopic Mass: 460.148 Da
• Topological Polar Surface Area: 202.000 Ų
• Heavy Atom Count: 33
• Formal Charge: 0
• Complexity: 1000.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 6
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1