P110 TFA - 10mM in DMSO , CAS No.P110(DMSO)

CAS: P110(DMSO) Cat. No.: P580476 Formula: C₁₀₀H₁₇₉N₄₅O₂₅(free) Peso molecolare: 2411.78(free)

QUALITÀ & PUREZZA 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

Information

P110 P110 is a dynamin-related protein 1 (Drp1) -specific inhibitor that binds directly to Drp1.

Targets

Drp1

In vitro

P110 is a Drp1-specific inhibitor that binds directly to Drp1. In some cases, this binding inhibits translocation to the mitochondria or prevents mitochondrial docking.

In vivo

P110 treatment inhibits the interaction of fission proteins Fis1/Drp1, decreases mitochondrial fission, and improves bioenergetics in three different rat models of IR, including primary cardiomyocytes, ex vivo heart model, and an in vivo myocardial infarction model.

Cell Research(from reference)

Cell lines：Primary cardiac myocytes 

Concentrations：1 μmol/L 

Incubation Time：2h + 2 to 60 min 

Specifiche

Specifiche e purezza

10mM in DMSO

Meccanismi biochimici e fisiologici

P110 is a dynamin-related protein 1 (Drp1)-specific inhibitor that binds directly to Drp1.

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Nomi e identificatori

Peso molecolare

2411.78(free)

Proprietà chimiche e fisiche

• Solubilità: Solubility (25°C) In vitro DMSO: 100 mg/mL (41.46 mM); Water: 100 mg/mL (41.46 mM); Ethanol: Insoluble