Palmitic acid N-hydroxysuccinimide ester - ≥98% , CAS No.14464-31-4

CAS: 14464-31-4 Cat. No.: P587261 Formula: C₂₀H₃₅NO₄ Peso molecolare: 353.5 Beilstein Registry Number: 1547410 Numero EC: 116-950-5 PubChem CID: 4620598

GRADE & PURITY ≥98%

Synonyms

2,5-Pyrrolidinedione, 1-[(1-oxohexadecyl)oxy]- | succinimidyl palmitate | DTXSID90404977 | AMY4566 | Palmitic acid N-hydroxysuccinimide ester, >=98% (TLC) | ZB0998 | AS-55028 | A855544 | FT-0674723 | N-palmitoyloxy-Succinimide | Hexadecanoic acid, 2,5-dio

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Application

Drug Delivery, Surface Modification, PEGylation of Protein, Peptide & Oligo

Panoramica

Application：

Palmitic acid N-hydroxysuccinimide ester has been used to couple a protein for fabrication of targeted delivery vehicles. It has also been used in the covalent attachment of palmitic acid to ovalbumin. Useful in the synthesis of hexadecanoyl derivatives of amino- and thio-compounds such as amino acids, aminoacyl-tRNA, coenzyme A, thioglycolic acid, etc.

Specifications

Sinonimi

2,5-Pyrrolidinedione, 1-[(1-oxohexadecyl)oxy]- | succinimidyl palmitate | DTXSID90404977 | AMY4566 | Palmitic acid N-hydroxysuccinimide ester, >=98% (TLC) | ZB0998 | AS-55028 | A855544 | FT-0674723 | N-palmitoyloxy-Succinimide | Hexadecanoic acid, 2,5-dio

Specifiche e purezza

≥98%

Meccanismi biochimici e fisiologici

Palmitic acid N-hydroxysuccinimide ester is used in the covalent linking of protein to palmitic acid.

Condizioni di conservazione di stoccaggio

Store at -20°C,Argon charged

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Purezza

≥98%

Nomi e identificatori

• Sorrisi canonici: CCCCCCCCCCCCCCCC(=O)ON1C(=O)CCC1=O
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) hexadecanoate
• InChIKey: OTNHQVHEZCBZQU-UHFFFAOYSA-N
• INCHI: 1S/C20H35NO4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-20(24)25-21-18(22)16-17-19(21)23/h2-17H2,1H3
• Isomeri SMILES: CCCCCCCCCCCCCCCC(=O)ON1C(=O)CCC1=O
• WGK Germania: 3
• PubChem CID: 4620598
• Peso molecolare: 353.5
• Beilstein: 1547410

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Pyrrolidines
      • Subclass Pyrrolidones

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Pyrrolidines
• Subclass: Pyrrolidones
• Intermediate Tree Nodes: Not available
• Direct Parent: Pyrrolidine-2-ones
• Alternative Parents: Dicarboximides Lactams Monocarboxylic acids and derivatives Azacyclic compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: 2-pyrrolidone - Dicarboximide - Lactam - Azacycle - Monocarboxylic acid or derivatives - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Carbonyl group - Aliphatic heteromonocyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as pyrrolidine-2-ones. These are pyrrolidines which bear a C=O group at position 2 of the pyrrolidine ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Proprietà chimiche e fisiche

• Punto di fusione (°C): 86℃
• Peso molecolare: 353.500 g/mol
• XLogP3: 6.600
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 16
• Exact Mass: 353.257 Da
• Monoisotopic Mass: 353.257 Da
• Topological Polar Surface Area: 63.700 Ų
• Heavy Atom Count: 25
• Formal Charge: 0
• Complexity: 393.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Riferimenti

1. Zhen Zhang, Hanqing Qian, Jie Huang, Huizi Sha, Hang Zhang, Lixia Yu, Baorui Liu, Dong Hua, Xiaoping Qian.  (2018)  Anti-EGFR-iRGD recombinant protein modified biomimetic nanoparticles loaded with gambogic acid to enhance targeting and antitumor ability in colorectal cancer treatment.  International Journal of Nanomedicine,      [PMID:30214200] [10.2147/IJN.S170148]