for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Panoramica
PARP10-IN-3 is a selective mono‐ADP‐ribosyltransferase PARP10 inhibitor with an IC 50 of 480 nM for human PARP10 . PARP10-IN-3 reveals potent inhibition on PARP2 and PARP15 with IC 50 s of 1.7 μM for human PARP2 and human PARP15 , respectively
In Vitro
PARP10-IN-3 (compound 20) has an IC 50 of 1-2 μM by olony‐formation assay (CFA) in HeLa‐PARP10 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
IC50& Target:human PARP10 480 nM (IC 50 ) human PARP2 1.7 μM (IC 50 ) human PARP15 1.7 μM (IC 50 ) human TNKS2 6.5 μM (IC 50 ) human PARP4 7 μM (IC 50 ) human TNKS1 21 μM (IC 50 ) human PARP14 41 μM (IC 50 ) human PARP12 >10 μM (IC 50 ) human PARP16 >10 μM (IC 50 ) human PARP1 >100 μM (IC 50 ) human PARP3 >100 μM (IC 50 )
Specifications
Meccanismi biochimici e fisiologici
PARP10-IN-3 is a selective mono‐ADP‐ribosyltransferase PARP10 inhibitor with an IC 50 of 480 nM for human PARP10 . PARP10-IN-3 reveals potent inhibition on PARP2 and PARP15 with IC 50 s of 1.7 μM for human PARP2 and human PARP15 , respectively.
Condizioni di conservazione di stoccaggio
Store at -20°C
Spedito in
Ice chest + Ice pads
Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.
Tipo di azione
INHIBITOR
Nomi e identificatori
Peso molecolare
256.26
Documentazione
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Certificati (CoA, COO, BSE/TSE e tabella di analisi)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
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Recensioni
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Domande frequenti
How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 2225800-19-9, the molecular formula is C14H12N2O3, and the molecular weight is 256.26 g/mol.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
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