PARPi-FL - ≥98% , CAS No.1380359-84-1

CAS: 1380359-84-1 Cat. No.: P286654 Formula: C₃₄H₃₂BF₃N₆O₃ Peso molecolare: 640.46 PubChem CID: 70697686

QUALITÀ & PUREZZA ≥98%

Synonyms

Boron, (4-((3-((4-(3-(5-((3,5-dimethyl-2H-pyrrol-2-ylidene-kappaN)methyl)-1H-pyrrol-2-yl-kappaN)-1-oxopropyl)-1-piperazinyl)carbonyl)-4-fluorophenyl)methyl)-1(2H)-phthalazinonato)difluoro-, (T-4)- | 1380359-84-1 | 4-[[3-[4-[3-(2,2-difluoro-10,12-dimethyl-

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Specifiche

Sinonimi

Boron, (4-((3-((4-(3-(5-((3,5-dimethyl-2H-pyrrol-2-ylidene-kappaN)methyl)-1H-pyrrol-2-yl-kappaN)-1-oxopropyl)-1-piperazinyl)carbonyl)-4-fluorophenyl)methyl)-1(2H)-phthalazinonato)difluoro-, (T-4)- | 1380359-84-1 | 4-[[3-[4-[3-(2,2-difluoro-10,12-dimethyl-

Specifiche e purezza

≥98%

Meccanismi biochimici e fisiologici

Fluorescent potent PARP inhibitor (IC50= 12 nM). Composed of a PARP inhibitor conjugated toBDY FL, SE. Colocalizes with PARP immunostaining in multiple cancer cell linesin vivoand accumulates in tumor cells and tumor associated macrophages. Enables high t

Condizioni di conservazione di stoccaggio

Protected from light,Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Tipo di azione

INHIBITOR

Purezza

≥98%

Nomi e identificatori

Sorrisi canonici

[B-]1(N2C(=CC(=C2C=C3[N+]1=C(C=C3)CCC(=O)N4CCN(CC4)C(=O)C5=C(C=CC(=C5)CC6=NNC(=O)C7=CC=CC=C76)F)C)C)(F)F

IUPAC Name

4-[[3-[4-[3-(2,2-difluoro-10,12-dimethyl-1-aza-3-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-3,5,7,9,11-pentaen-4-yl)propanoyl]piperazine-1-carbonyl]-4-fluorophenyl]methyl]-2H-phthalazin-1-one

InChIKey

IGUTVNUEFKPBGK-UHFFFAOYSA-N

INCHI

1S/C34H32BF3N6O3/c1-21-17-22(2)43-31(21)20-25-9-8-24(44(25)35(43,37)38)10-12-32(45)41-13-15-42(16-14-41)34(47)28-18-23(7-11-29(28)36)19-30-26-5-3-4-6-27(26)33(46)40-39-30/h3-9,11,17-18,20H,10,12-16,19H2,1-2H3,(H,40,46)

Isomeri SMILES

[B-]1(N2C(=CC(=C2C=C3[N+]1=C(C=C3)CCC(=O)N4CCN(CC4)C(=O)C5=C(C=CC(=C5)CC6=NNC(=O)C7=CC=CC=C76)F)C)C)(F)F

PubChem CID

70697686

Peso molecolare

640.46

Proprietà chimiche e fisiche

• Solubilità: Solvent:DMSO, Max Conc. mg/mL: 6.4, Max Conc. mM: 10
• Sensibilità: light sensitive

Domande frequenti

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C, protected from light. The material is light-sensitive — keep it in its original opaque or amber container.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1380359-84-1, the molecular formula is C??H??BF?N?O?, and the molecular weight is 640.46 g/mol. InChIKey IGUTVNUEFKPBGK-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.