GRADE & PURITYCarrier Free?Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays.Validated?Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated.ExactAb™?ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications.Azide Free?Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory.PBS Only?PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers.See COA
Carrier Free, ExactAb™, Azide Free, Validated, PBS Only, See COA
Meccanismi biochimici e fisiologici
Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
Specie ospite
Mouse
Specificità
PD-L1
Immunogeno
Full length Human PD-L1.
Controllo positivo
IHC-P: Human NSCLC tissue; PD L1 transfected HEK-293 cells. Human lung carcinoma and placenta tissue. mIHC: Human tonsil tissue. WB: CHO-PD-L1 (PD-L1 stably expressed Chinese hamster ovary epithelial cell) whole cell lysate. A549 treated with 100ng/ml IFN
Store at 2-8℃ long term (12 months). Do not freeze.
Immagini
PD-L1 Mouse mAb (Ab121019) - Flow Cytometry
Flow Cytometry analysis of MDA-MB-231 cells labelling PD-L1 (red) with PD-L1 Mouse mAb (Ab121019) at 0.2 μg/mL for 1 hour at 4°C and detected with AF488 - conjugated affinipure goat anti - Mouse IgG. Blue - Mouse IgG Isotype Control Antibody (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.
Applicazione
Applicazione
Dilution info
Flow Cytometry
Use at an assay dependent concentration.
Documentazione
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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