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· · COA & SDS Disponibile per ogni prodotto · Spedizione lo stesso giorno su articoli in magazzino PF 915275 - ≥98% (HPLC) , CAS No.857290-04-1
Synonyms
PF-915275; PF915275 | PF-915275 | SCHEMBL4384483 | BDBM29864 | N-(6-Amino-2-pyridinyl)-4'-cyano-[1,1'-biphenyl]-4-sulfonamide | BCP28049 | 4'-cyano-biphenyl-4-sulfonic acid (6-amino-pyridin-2-yl)-amide | EC-000.2428 | N-(Pyridin-2-yl) arylsulfonamide, 26
Storage
Conservare a -20°C
Shipped In
Cassetta del ghiaccio + cuscini per il ghiaccio
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Why this grade ≥98% (HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Conservare a -20°C Ships Cassetta del ghiaccio + cuscini per il ghiaccio Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Sinonimi
PF-915275; PF915275 | PF-915275 | SCHEMBL4384483 | BDBM29864 | N-(6-Amino-2-pyridinyl)-4'-cyano-[1,1'-biphenyl]-4-sulfonamide | BCP28049 | 4'-cyano-biphenyl-4-sulfonic acid (6-amino-pyridin-2-yl)-amide | EC-000.2428 | N-(Pyridin-2-yl) arylsulfonamide, 26
Specifiche e purezza
≥98% (HPLC)
Meccanismi biochimici e fisiologici
Inibitore potente e selettivo della 11β-idrossisteroide deidrogenasi di tipo 1 (11βHSD1) (Ki= 2,3 nM) che mostra scarsa attività nei confronti della 11βHSD2 (1,5% di inibizione a 10μM). Inibisce la conversione del prednisone in prednisolone negli epatocit
Condizioni di conservazione di stoccaggio
Conservare a -20°C
Spedito in
Cassetta del ghiaccio + cuscini per il ghiaccio
Nomi e identificatori Pubchem Sid 528766588 Sorrisi canonici C1=CC(=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)C3=CC=C(C=C3)C#N)N IUPAC Name N-(6-aminopyridin-2-yl)-4-(4-cyanophenyl)benzenesulfonamide InChIKey ZESFDAKNYJQYKO-UHFFFAOYSA-N INCHI 1S/C18H14N4O2S/c19-12-13-4-6-14(7-5-13)15-8-10-16(11-9-15)25(23,24)22-18-3-1-2-17(20)21-18/h1-11H,(H3,20,21,22) Isomeri SMILES C1=CC(=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)C3=CC=C(C=C3)C#N)N PubChem CID 23725123 Peso molecolare 350.39
Documentazione 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Benzenoids Classe Benzene and substituted derivatives Subclass Biphenyls and derivatives Intermediate Tree Nodes Not available Direct Parent Biphenylcarbonitriles Alternative Parents Benzenesulfonamides Benzenesulfonyl compounds Benzonitriles Aminopyridines and derivatives Organosulfonamides Imidolactams Heteroaromatic compounds Aminosulfonyl compounds Nitriles Azacyclic compounds Primary amines Organic oxides Hydrocarbon derivatives Molecular Framework Aromatic heteromonocyclic compounds Substituents Biphenylcarbonitrile - Benzenesulfonamide - Benzenesulfonyl group - Benzonitrile - Aminopyridine - Pyridine - Imidolactam - Organosulfonic acid amide - Heteroaromatic compound - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Aminosulfonyl compound - Sulfonyl - Carbonitrile - Nitrile - Azacycle - Organoheterocyclic compound - Organosulfur compound - Organonitrogen compound - Organic nitrogen compound - Amine - Organic oxide - Cyanide - Primary amine - Hydrocarbon derivative - Organic oxygen compound - Aromatic heteromonocyclic compound Descrizione This compound belongs to the class of organic compounds known as biphenylcarbonitriles. These are organic compounds containing an acetonitrile with one hydrogen replaced by a biphenyl group. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Struttura 3D Obiettivi associati (umani) Obiettivi associati (non umani) Meccanismi d'azione Certificati (CoA, COO, BSE/TSE e tabella di analisi) Proprietà chimiche e fisiche Solubilità Solvent:DMSO, Max Conc. mg/mL: 35.04, Max Conc. mM: 100 Peso molecolare 350.400 g/mol XLogP3 2.700 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 4 Exact Mass 350.084 Da Monoisotopic Mass 350.084 Da Topological Polar Surface Area 117.000 Ų Heavy Atom Count 25 Formal Charge 0 Complexity 578.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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