Phellopterin - ≥99% , CAS No.2543-94-4

CAS: 2543-94-4 Cat. No.: P649249 Formula: C₁₇H₁₆O₅ Peso molecolare: 300.31 Numero EC: 110-046-4

QUALITÀ & PUREZZA ≥99%

Synonyms

Q3742334 | NSC 152469 | NSC152469 | NSC-152469 | Methanesulfinic acid, 1,1,1-trifluoro-, sodium salt (1:1) | 4-Methoxy-9-prenyloxypsoralen | C17047 | HMS2203M11 | Phelloptorin | NCGC00247535-01 | 4-Methoxy-9-((3-methylbut-2-en-1-yl)oxy)-7H-furo[3,2-g]chro

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Panoramica

Phellopterin is a natural product isolated from Angelica dahurica. Phellopterin reduces TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium.

Form:Solid

Specifiche

Sinonimi

Q3742334 | NSC 152469 | NSC152469 | NSC-152469 | Methanesulfinic acid, 1,1,1-trifluoro-, sodium salt (1:1) | 4-Methoxy-9-prenyloxypsoralen | C17047 | HMS2203M11 | Phelloptorin | NCGC00247535-01 | 4-Methoxy-9-((3-methylbut-2-en-1-yl)oxy)-7H-furo[3,2-g]chro

Specifiche e purezza

≥99%

Meccanismi biochimici e fisiologici

Phellopterin is a natural product isolated from Angelica dahurica . Phellopterin reduces TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium.

Condizioni di conservazione di stoccaggio

Protected from light,Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Purezza

≥99%

Nomi e identificatori

Pubchem Sid

528773295

Sorrisi canonici

COc1c2ccoc2c(OCC=C(C)C)c2oc(=O)ccc12

IUPAC Name

4-methoxy-9-(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one

InChIKey

BMLZFLQMBMYVHG-UHFFFAOYSA-N

INCHI

1S/C17H16O5/c1-10(2)6-8-21-17-15-12(7-9-20-15)14(19-3)11-4-5-13(18)22-16(11)17/h4-7,9H,8H2,1-3H3

Isomeri SMILES

CC(=CCOC1=C2C(=C(C3=C1OC(=O)C=C3)OC)C=CO2)C

CAS alternativo

2543-94-4

Numero NSC

152469

Termini MeSH

phellopterin

Peso molecolare

300.31

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Phenylpropanoids and polyketides
    • Classe Coumarins and derivatives
      • Subclass Furanocoumarins
        • Level5 Linear furanocoumarins
          • Level6 Psoralens
            • Level7 5-methoxypsoralens

• Kingdom: Organic compounds
• Superclass: Phenylpropanoids and polyketides
• Classe: Coumarins and derivatives
• Subclass: Furanocoumarins
• Intermediate Tree Nodes: Linear furanocoumarins - Psoralens
• Direct Parent: 5-methoxypsoralens
• Alternative Parents: 1-benzopyrans Benzofurans Anisoles Pyranones and derivatives Alkyl aryl ethers Heteroaromatic compounds Furans Lactones Oxacyclic compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: 5-methoxypsoralen - Benzopyran - 1-benzopyran - Benzofuran - Anisole - Alkyl aryl ether - Pyranone - Pyran - Benzenoid - Furan - Heteroaromatic compound - Lactone - Oxacycle - Ether - Organoheterocyclic compound - Organic oxygen compound - Organooxygen compound - Hydrocarbon derivative - Organic oxide - Aromatic heteropolycyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as 5-methoxypsoralens. These are psoralens containing a methoxy group attached at the C5 position of the psoralen group.
• External Descriptors: psoralens

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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Meccanismi d'azione

Proprietà chimiche e fisiche

• Solubilità: DMSO : 100 mg/mL (332.99 mM; Need ultrasonic)
• Sensibilità: Light sensitive
• Peso molecolare: 300.300 g/mol
• XLogP3: 3.800
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 300.1 Da
• Monoisotopic Mass: 300.1 Da
• Topological Polar Surface Area: 57.900 Ų
• Heavy Atom Count: 22
• Formal Charge: 0
• Complexity: 479.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1