Picloxydine - ≥98% , CAS No.5636-92-0

CAS: 5636-92-0 Cat. No.: P649325 Formula: C₂₀H₂₄Cl₂N₁₀ Peso molecolare: 475.38 Numero EC: 227-084-3 PubChem CID: 5748610

GRADE & PURITY ≥98%

Synonyms

PICLOXYDINE [WHO-DD] | Picloxydinum [INN-Latin] | CHEBI:135768 | DB13607 | Picloxydinum | UNII-4YC2PY3AEU | N1,N4-Bis(N-(4-chlorophenyl)carbamimidoyl)piperazine-1,4-bis(carboximidamide) | Picloxidina [INN-Spanish] | Picloxydine | PICLOXYDINE [INN] | EINEC

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Panoramica

Picloxydine is a heterocyclic biguanide with antibacterial and antiplaque activity.

In Vivo

0.4% Picloxydine produces a highly significant drop in the number of aerobic organisms. 0.4% Picloxydine is far more effective than 0.2% Picloxydine or chlorhexidine in reducing the total viable count of oral aerobic and anaerobic organisms . Picloxydine is also used in eye drops in the topical therapy of trachoma. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:Bacterial

Specifications

Sinonimi

PICLOXYDINE [WHO-DD] | Picloxydinum [INN-Latin] | CHEBI:135768 | DB13607 | Picloxydinum | UNII-4YC2PY3AEU | N1,N4-Bis(N-(4-chlorophenyl)carbamimidoyl)piperazine-1,4-bis(carboximidamide) | Picloxidina [INN-Spanish] | Picloxydine | PICLOXYDINE [INN] | EINEC

Specifiche e purezza

≥98%

Meccanismi biochimici e fisiologici

Picloxydine is a heterocyclic biguanide with antibacterial and antiplaque activity.

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Tipo di azione

INHIBITOR

Purezza

≥98%

Nomi e identificatori

• Sorrisi canonici: C1CN(CCN1C(=NC(=NC2=CC=C(C=C2)Cl)N)N)C(=NC(=NC3=CC=C(C=C3)Cl)N)N
• IUPAC Name: 1-N',4-N'-bis[N'-(4-chlorophenyl)carbamimidoyl]piperazine-1,4-dicarboximidamide
• InChIKey: YNCLPFSAZFGQCD-UHFFFAOYSA-N
• INCHI: 1S/C20H24Cl2N10/c21-13-1-5-15(6-2-13)27-17(23)29-19(25)31-9-11-32(12-10-31)20(26)30-18(24)28-16-7-3-14(22)4-8-16/h1-8H,9-12H2,(H4,23,25,27,29)(H4,24,26,28,30)
• Isomeri SMILES: C1N(CCN(C1)/C(=N/C(=NC2=CC=C(C=C2)Cl)N)/N)/C(=N/C(=NC3=CC=C(C=C3)Cl)N)/N
• CAS alternativo: 5636-92-0
• PubChem CID: 5748610
• Termini MeSH: 1,1-(p-chlorophenylguanidinoformimidonyl)bis piperazine;picloxidine;picloxydine;picloxydine dihydrochloride;Vitabact
• Peso molecolare: 475.38

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Benzene and substituted derivatives
      • Subclass Halobenzenes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Benzene and substituted derivatives
• Subclass: Halobenzenes
• Intermediate Tree Nodes: Not available
• Direct Parent: Chlorobenzenes
• Alternative Parents: Biguanides Piperazines Aryl chlorides Propargyl-type 1,3-dipolar organic compounds Carboximidamides Azacyclic compounds Organopnictogen compounds Organochlorides Imines Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Biguanide - Chlorobenzene - Aryl chloride - Aryl halide - 1,4-diazinane - Piperazine - Guanidine - Azacycle - Organoheterocyclic compound - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Carboximidamide - Imine - Organopnictogen compound - Organic nitrogen compound - Organohalogen compound - Organochloride - Organonitrogen compound - Hydrocarbon derivative - Aromatic heteromonocyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as chlorobenzenes. These are compounds containing one or more chlorine atoms attached to a benzene moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Proprietà chimiche e fisiche

• Solubilità: DMSO : 11.36 mg/mL (23.90 mM; ultrasonic and warming and adjust pH to 5 with HCl and heat to 60°C)
• Peso molecolare: 475.400 g/mol
• XLogP3: 1.800
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 474.156 Da
• Monoisotopic Mass: 474.156 Da
• Topological Polar Surface Area: 160.000 Ų
• Heavy Atom Count: 32
• Formal Charge: 0
• Complexity: 667.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 2
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 2
• Covalently-Bonded Unit Count: 1

Domande frequenti

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 5636-92-0, the molecular formula is C20H24Cl2N10, and the molecular weight is 475.38 g/mol. InChIKey YNCLPFSAZFGQCD-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.