Poloxamer 407 - purified, non-ionic , CAS No.9003-11-6

CAS: 9003-11-6 Cat. No.: P434419 Numero EC: 618-355-0

GRADE & PURITY purified, non-ionic

Synonyms

Emkalyx L101 | Pluronic F 68 | Regulaid | Magcyl | Pluronic L 64 | Pronon 204 | Teric PE60 | Pluronic F 38 | Pluronic L | Teric PE40 | Pluronic L44 | Pluronic P-75 | Rokopol 30P9 | Slovanik 630 | Hydrowet | Pluronic 31R2 | Pluronic L 68 | Monolan PB | Plu

Storage

Store at 2-8°C

Shipped In

Wet ice

Panoramica

Poloxamer 407 is a water-soluble, non-ionic surfactant with low toxicity and good solubilizing capacity. This triblock copolymer is composed of a hydrophobic residue of polyoxypropylene (POP) flanked by two hydrophilic units of polyoxyethylene (POE).

Application：

as an inhibitor of lipoprotein lipase activity to assess hepatic very-low-density lipoprotein (VLDL)- triglyceride (TG) secretion in mice；for VLDL secretion assay in mice；to intraperitoneally inject the mice by dissolving in phosphate buffer saline (PBS) for hepatic triglyceride production  

Specifications

Sinonimi

Emkalyx L101 | Pluronic F 68 | Regulaid | Magcyl | Pluronic L 64 | Pronon 204 | Teric PE60 | Pluronic F 38 | Pluronic L | Teric PE40 | Pluronic L44 | Pluronic P-75 | Rokopol 30P9 | Slovanik 630 | Hydrowet | Pluronic 31R2 | Pluronic L 68 | Monolan PB | Plu

Specifiche e purezza

purified, non-ionic

Meccanismi biochimici e fisiologici

Poloxamer 407 (P407) exhibits reversible gelation properties above a particular polymer concentration and temperature. Poloxamer 407-based sterile injectable formulations serve to be a good candidate for drug delivery. P407 thermo-responsive hydrogels are

Condizioni di conservazione di stoccaggio

Store at 2-8°C

Spedito in

Wet ice

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Nomi e identificatori

• Pubchem Sid: 508814478
• Sorrisi canonici: CC1CO1.C1CO1
• IUPAC Name: 2-methyloxirane;oxirane
• InChIKey: RVGRUAULSDPKGF-UHFFFAOYSA-N
• INCHI: 1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2
• Isomeri SMILES: CC1CO1.C1CO1
• CAS alternativo: 691397-13-4
• Reaxy-Rn: 13268566
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=13268566&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Epoxides

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Epoxides
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Epoxides
• Alternative Parents: Oxacyclic compounds Dialkyl ethers Hydrocarbon derivatives
• Molecular Framework: Not available
• Substituents: Oxacycle - Ether - Oxirane - Dialkyl ether - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aliphatic heteromonocyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as epoxides. These are compounds containing a cyclic ether with three ring atoms(one oxygen and two carbon atoms).
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Proprietà chimiche e fisiche

• Solubilità: soluble, clear, colorless
• Indice di rifrazione: 1.459
• Punto di ebollizione (°C): > 149 °C
• Punto di fusione (°C): 40-50 °C
• Peso molecolare: 102.130 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 102.068 Da
• Monoisotopic Mass: 102.068 Da
• Topological Polar Surface Area: 25.100 Ų
• Heavy Atom Count: 7
• Formal Charge: 0
• Complexity: 36.700
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3