Pozanicline , Neuronal acetylcholine receptor; alpha6/beta2 partial agonist, CAS No.161417-03-4, Neuronal acetylcholine receptor; alpha6/beta2 partial agonist

CAS: 161417-03-4 Cat. No.: P670975 Molecular Weight: 192.26 PubChem CID: 178052
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Synonyms
Pozanicline | PDSP1_001326 | 2-methyl-3-{[(2S)-pyrrolidin-2-yl]methoxy}pyridine | 2-methyl-3-[[(2S)-pyrrolidin-2-yl]methoxy]pyridine | D09367 | POZANICLINE [WHO-DD] | 2-Methyl-3-(2S-pyrrolidinylmethoxy)pyridine | DB05458 | UNII-CL2002R563 | Pyridine, 2-me
Storage
Room temperature
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Size
Status
Price
Qty
1mg
P670975-1mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$999.90
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Why this grade

for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature Ships Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
Pozanicline | PDSP1_001326 | 2-methyl-3-{[(2S)-pyrrolidin-2-yl]methoxy}pyridine | 2-methyl-3-[[(2S)-pyrrolidin-2-yl]methoxy]pyridine | D09367 | POZANICLINE [WHO-DD] | 2-Methyl-3-(2S-pyrrolidinylmethoxy)pyridine | DB05458 | UNII-CL2002R563 | Pyridine, 2-me
Storage
Room temperature
Action Type
PARTIAL AGONIST
Mechanism of action
Neuronal acetylcholine receptor; alpha6/beta2 partial agonist
Product Properties
ALogP1.3
Names and Identifiers
Canonical SmilesCC1=C(C=CC=N1)OCC2CCCN2
IUPAC Name2-methyl-3-[[(2S)-pyrrolidin-2-yl]methoxy]pyridine
InChIKeyYRVIKLBSVVNSHF-JTQLQIEISA-N
INCHI1S/C11H16N2O/c1-9-11(5-3-6-12-9)14-8-10-4-2-7-13-10/h3,5-6,10,13H,2,4,7-8H2,1H3/t10-/m0/s1
Isomeric SMILES CC1=C(C=CC=N1)OC[C@@H]2CCCN2
PubChem CID 178052
Molecular Weight 192.26

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic oxygen compounds
ClassOrganooxygen compounds
SubclassEthers
Intermediate Tree Nodes Not available
Direct ParentAlkyl aryl ethers
Alternative Parents Methylpyridines  Pyrrolidines  Heteroaromatic compounds  Dialkylamines  Azacyclic compounds  Organopnictogen compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Methylpyridine - Alkyl aryl ether - Pyridine - Heteroaromatic compound - Pyrrolidine - Azacycle - Organoheterocyclic compound - Secondary amine - Secondary aliphatic amine - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Amine - Aromatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as alkyl aryl ethers. These are organic compounds containing the alkyl aryl ether functional group with the generic formula R-O-R' , where R is an alkyl group and R' is an aryl group.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
CHRNA7 Tchem Neuronal acetylcholine receptor protein alpha-7 subunit (3524 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRND Tclin Acetylcholine receptor protein delta chain (14 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
IMR-32 (1082 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRNB2 Tclin Neuronal acetylcholine receptor; alpha4/beta2 (3972 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Canis familiaris (36305 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Chrna3 Neuronal acetylcholine receptor; alpha3/beta4 (1368 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Chrna3 Neuronal acetylcholine receptor (756 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
Molecular Weight192.260 g/mol
XLogP31.300
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Exact Mass192.126 Da
Monoisotopic Mass192.126 Da
Topological Polar Surface Area34.200 Ų
Heavy Atom Count14
Formal Charge0
Complexity175.000
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
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