Prodipine hydrochloride - ≥99% , CAS No.31314-39-3

CAS: 31314-39-3 Cat. No.: P651099 Formula: C₂₀H₂₆ClN Peso molecolare: 315.9 PubChem CID: 3030531

QUALITÀ & PUREZZA ≥99%

Synonyms

Prodipine hydrochloride [MI]|1-Isopropyl-4,4-diphenylpiperidine hydrochloride|NIOSH/TM7755000|Prodipine hydrochloride|Piperidine, 4,4-diphenyl-1-isopropyl-, hydrochloride|BY-101|Piperidine, 1-(1-methylethyl)-4,4-diphenyl-, hydrochloride (1:1)|4,4-Diphenyl-1-isopropylpiperidine hydrochloride|3,3-Diphenylpiperidine, HCl|ANTHEN|4,4-diphenyl-1-propan-2-ylpiperidine;hydrochloride

Storage

Store at 2-8°C,Desiccated

Shipped In

Wet ice

Panoramica

Prodipine, a diphenyl-phosphonate derivative. The IC 50 s of Prodipine for purified and plasma Dipeptidyl peptidase IV ( DPP IV ) from the rabbit are 4.5 μM and 30 μM, respectively.

In Vitro

Prodipine, a diphenyl-phosphonate derivative selected from a group of slow-binding irreversible inhibitors of this enzyme. The IC 50 values of Prodipine for purified and plasma DPP IV from the rabbit are 4.5 μM and 30 μM, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Male rabbits weighing 3-4 kg receive a single intravenous injection with 10 mg Prodipine or saline. After 1 hr, plasma DPP IV activity has decreased to less than 20% of the preinjection value and remaines unchanged during a 24 hr observation period. A profound and long-lasting inhibition of plasma DPP IV activity is observed in the treated animals (1, 5 or 10 mg). It takes 5 to 8 days to reach half of the pretreatment DPP IV activity and generally more than 20 days for a complete recovery . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:IC50: 4.5 μM (purified DPP IV), 30 μM (plasma DPP IV)

Specifiche

Sinonimi

Prodipine hydrochloride [MI] | 1-Isopropyl-4,4-diphenylpiperidine hydrochloride | NIOSH/TM7755000 | Prodipine hydrochloride | Piperidine, 4,4-diphenyl-1-isopropyl-, hydrochloride | BY-101 | Piperidine, 1-(1-methylethyl)-4,4-diphenyl-, hydrochloride (1:1) | 4,4-Diphenyl-1-isopropylpiperidine hydrochloride | 3,3-Diphenylpiperidine, HCl | AN Mostra altro

Specifiche e purezza

≥99%

Meccanismi biochimici e fisiologici

Prodipine, a diphenyl-phosphonate derivative. The IC 50 s of Prodipine for purified and plasma Dipeptidyl peptidase IV ( DPP IV ) from the rabbit are 4.5 μM and 30 μM, respectively.

Condizioni di conservazione di stoccaggio

Store at 2-8°C,Desiccated

Spedito in

Wet ice

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Purezza

≥99%

Nomi e identificatori

Sorrisi canonici

CC(C)N1CCC(CC1)(C2=CC=CC=C2)C3=CC=CC=C3.Cl

IUPAC Name

4,4-diphenyl-1-propan-2-ylpiperidine;hydrochloride

InChIKey

ZFCBOUXJVGNRIF-UHFFFAOYSA-N

INCHI

1S/C20H25N.ClH/c1-17(2)21-15-13-20(14-16-21,18-9-5-3-6-10-18)19-11-7-4-8-12-19;/h3-12,17H,13-16H2,1-2H3;1H

Isomeri SMILES

CC(C)N1CCC(CC1)(C2=CC=CC=C2)C3=CC=CC=C3.Cl

PubChem CID

3030531

Peso molecolare

315.9

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Benzene and substituted derivatives
      • Subclass Diphenylmethanes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Benzene and substituted derivatives
• Subclass: Diphenylmethanes
• Intermediate Tree Nodes: Not available
• Direct Parent: Diphenylmethanes
• Alternative Parents: Phenylpiperidines Aralkylamines Trialkylamines Azacyclic compounds Hydrochlorides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Diphenylmethane - Phenylpiperidine - Aralkylamine - Piperidine - Tertiary aliphatic amine - Tertiary amine - Azacycle - Organoheterocyclic compound - Organic nitrogen compound - Hydrocarbon derivative - Hydrochloride - Organonitrogen compound - Amine - Aromatic heteromonocyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as diphenylmethanes. These are compounds containing a diphenylmethane moiety, which consists of a methane wherein two hydrogen atoms are replaced by two phenyl groups.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Proprietà chimiche e fisiche

• Peso molecolare: 315.900 g/mol
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 315.175 Da
• Monoisotopic Mass: 315.175 Da
• Topological Polar Surface Area: 3.200 Ų
• Heavy Atom Count: 22
• Formal Charge: 0
• Complexity: 282.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

Domande frequenti

What is the purity of this product?

This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at 2–8 °C, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 31314-39-3, the molecular formula is C20H26ClN, and the molecular weight is 315.9 g/mol. InChIKey ZFCBOUXJVGNRIF-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.