Propranolol hydrochloride - ≥98% , CAS No.3506-09-0

CAS: 3506-09-0 Cat. No.: P303508 Formula: C₁₆H₂₂ClNO₂ Peso molecolare: 295.81 Numero EC: 222-501-5

GRADE & PURITY ≥98%

Synonyms

Noloten | Dibudinate | Panolol | Propral | Pur-Bloka | Sloprolol | Dumopranol | Hemipralon | Herzbase | Propabloc | InnoPran XL | Tesnol | Procor | Prosin | Sawatol | Anaprilin | Angilol | Kidoral | Sinal | Pylapron | Sudenol | DTXSID3021198 | Obsidan | P

Storage

Store at 2-8°C

Shipped In

Wet ice

Panoramica

Propranolol hydrochloride is a nonselective and BBB-permeableβ-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively. Propranolol hydrochloride inhibits [3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM. Propranolol hydrochloride is used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy；

Specifications

Sinonimi

Noloten | Dibudinate | Panolol | Propral | Pur-Bloka | Sloprolol | Dumopranol | Hemipralon | Herzbase | Propabloc | InnoPran XL | Tesnol | Procor | Prosin | Sawatol | Anaprilin | Angilol | Kidoral | Sinal | Pylapron | Sudenol | DTXSID3021198 | Obsidan | P

Specifiche e purezza

≥98%

Condizioni di conservazione di stoccaggio

Store at 2-8°C

Spedito in

Wet ice

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Purezza

≥98%

Nomi e identificatori

Pubchem Sid

508815057

Sorrisi canonici

CC(C)NCC(COC1=CC=CC2=CC=CC=C21)O.Cl

IUPAC Name

1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol;hydrochloride

InChIKey

ZMRUPTIKESYGQW-UHFFFAOYSA-N

INCHI

1S/C16H21NO2.ClH/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16;/h3-9,12,14,17-18H,10-11H2,1-2H3;1H

Isomeri SMILES

CC(C)NCC(COC1=CC=CC2=CC=CC=C21)O.Cl

CAS alternativo

318-98-9

Peso molecolare

295.81

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Naphthalenes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Naphthalenes
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Naphthalenes
• Alternative Parents: Alkyl aryl ethers Secondary alcohols 1,2-aminoalcohols Dialkylamines Organopnictogen compounds Hydrochlorides Hydrocarbon derivatives
• Molecular Framework: Aromatic homopolycyclic compounds
• Substituents: Naphthalene - Alkyl aryl ether - 1,2-aminoalcohol - Secondary alcohol - Secondary aliphatic amine - Ether - Secondary amine - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Hydrochloride - Hydrocarbon derivative - Organopnictogen compound - Amine - Organic oxygen compound - Alcohol - Aromatic homopolycyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as naphthalenes. These are compounds containing a naphthalene moiety, which consists of two fused benzene rings.
• External Descriptors: hydrochloride

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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Meccanismi d'azione

Proprietà chimiche e fisiche

• Peso molecolare: 295.800 g/mol
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 295.134 Da
• Monoisotopic Mass: 295.134 Da
• Topological Polar Surface Area: 41.500 Ų
• Heavy Atom Count: 20
• Formal Charge: 0
• Complexity: 257.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3