Rabeprazole sodium - ≥98%(HPLC) , CAS No.117976-90-6

CAS: 117976-90-6 Cat. No.: R138070 Formula: C₁₈H₂₀N₃O₃S · Na Peso molecolare: 381.42 Numero EC: 629-730-3 PubChem CID: 14720269

QUALITÀ & PUREZZA ≥98%(HPLC)

Synonyms

Rabeprazole SodiumDR | sodium;2-[[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methylsulfinyl]benzimidazol-1-ide | AS-13338 | FT-0689461 | HMS3373B05 | 3-Ethyl-2-methyl-5-(morpholinomethyl)-6,7-dihydro-1H-indol-4(5H)-one hydrochloride | AKOS015895734 | DTXSI

Storage

Room temperature

Shipped In

Normal

Specifiche

Sinonimi

Rabeprazole SodiumDR | sodium;2-[[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methylsulfinyl]benzimidazol-1-ide | AS-13338 | FT-0689461 | HMS3373B05 | 3-Ethyl-2-methyl-5-(morpholinomethyl)-6,7-dihydro-1H-indol-4(5H)-one hydrochloride | AKOS015895734 | DTXSI

Specifiche e purezza

≥98%(HPLC)

Meccanismi biochimici e fisiologici

Potent and selective irreversible gastric H + /K + ATPase pump inhibitor (IC 50 = 72 nM). Prodrug of sulphenamide. Activates over a greater pH range than omeprazole. Shows antibacterial effects against H. pylori (IC 50 = 290 nM).

Condizioni di conservazione di stoccaggio

Room temperature

Spedito in

Normal

Tipo di azione

INHIBITOR

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purezza

≥98%(HPLC)

Nomi e identificatori

Pubchem Sid

504767702

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504767702

Sorrisi canonici

CC1=C(C=CN=C1CS(=O)C2=NC3=CC=CC=C3[N-]2)OCCCOC.[Na+]

IUPAC Name

sodium;2-[[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methylsulfinyl]benzimidazol-1-ide

InChIKey

KRCQSTCYZUOBHN-UHFFFAOYSA-N

INCHI

1S/C18H20N3O3S.Na/c1-13-16(19-9-8-17(13)24-11-5-10-23-2)12-25(22)18-20-14-6-3-4-7-15(14)21-18;/h3-4,6-9H,5,10-12H2,1-2H3;/q-1;+1

Isomeri SMILES

CC1=C(C=CN=C1CS(=O)C2=NC3=CC=CC=C3[N-]2)OCCCOC.[Na+]

WGK Germania

3

PubChem CID

14720269

Peso molecolare

381.42

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Benzimidazoles
      • Subclass Sulfinylbenzimidazoles

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Benzimidazoles
• Subclass: Sulfinylbenzimidazoles
• Intermediate Tree Nodes: Not available
• Direct Parent: Sulfinylbenzimidazoles
• Alternative Parents: Methylpyridines Alkyl aryl ethers Benzenoids Imidazoles Heteroaromatic compounds Sulfoxides Sulfinyl compounds Dialkyl ethers Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organic zwitterions Organic sodium salts Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Sulfinylbenzimidazole - Alkyl aryl ether - Methylpyridine - Pyridine - Benzenoid - Azole - Imidazole - Heteroaromatic compound - Sulfoxide - Dialkyl ether - Ether - Azacycle - Organic alkali metal salt - Sulfinyl compound - Organic nitrogen compound - Organic zwitterion - Organic salt - Organic sodium salt - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Aromatic heteropolycyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as sulfinylbenzimidazoles. These are polycyclic aromatic compounds containing a sulfinyl group attached at the position 2 of a benzimidazole moiety.
• External Descriptors: organic sodium salt

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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Meccanismi d'azione

Proprietà chimiche e fisiche

• Solubilità: Solubility in water: Completely soluble; Very soluble in Ethanol,Chloroform; Soluble in Methanol; Insoluble in Ether
• Sensibilità: Hygroscopic,Heat Sensitive
• Punto di fusione (°C): 150 °C
• Peso molecolare: 381.400 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 8
• Exact Mass: 381.112 Da
• Monoisotopic Mass: 381.112 Da
• Topological Polar Surface Area: 81.500 Ų
• Heavy Atom Count: 26
• Formal Charge: 0
• Complexity: 446.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3