10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Panoramica
PW0464, a nanomolar potent complete G protein biased ligand, is a noncatechol D1R agonist, with an EC 50 of 5.8 nM (Gs-cAMP).
In Vitro
PW0464 (compound 24) is found to elicit complete G protein bias, showing no activity for D1R-mediated β-arrestin recruitment. PW0464 (compound 24), the non-catechol agonist, forms bonds with S198 5.42 and S202 5.46 via its fluorine atom. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Specifications
Specifiche e purezza
10mM in DMSO
Meccanismi biochimici e fisiologici
PW0464, a nanomolar potent complete G protein biased ligand, is a noncatechol D1R agonist, with an EC 50 of 5.8 nM (Gs-cAMP).
Condizioni di conservazione di stoccaggio
Store at -80°C
Spedito in
Dry ice packs + Cold packs
Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.
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