Ranitidine - Moligand™, 10mM in DMSO , Antagonist of H 2 receptor, CAS No.66357-35-5, Antagonist of H 2 receptor

CAS: 66357-35-5 Cat. No.: R425343 Formula: C13H22N4O3S Peso molecolare: 314.39 Numero EC: 266-332-5 PubChem CID: 3001055
Disponibile su ordine
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
Synonyms
ranitidine|66357-35-5|Ranitidine Base|ranitidine hydrochloride|Coralen|Gastrial|Quantor|Raticina|Rantidine|ZANTAC|Ranisen|Ratic|Taural|Ranitidina|Ranitidinum|Mauran|Ranitidine free base|CHEBI:8776|Ranitidine Impurity J|1,1-Ethenediamine, N-(2-(((5-((dimet
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
Size
Germania (EU)
USA*
Price
Qty
1ml
R425343-1ml
1 Disponibile

89,29€

104,91€
Salva 15,62 € (14.89%)
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Why this grade

Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 14 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Sinonimi
ranitidine | 66357-35-5 | Ranitidine Base | ranitidine hydrochloride | Coralen | Gastrial | Quantor | Raticina | Rantidine | ZANTAC | Ranisen | Ratic | Taural | Ranitidina | Ranitidinum | Mauran | Ranitidine free base | CHEBI:8776 | Ranitidine Impurity J | 1,1-Ethenediamine, N-(2-(((5-((dimet
Specifiche e purezza
Moligand™, 10mM in DMSO
Condizioni di conservazione di stoccaggio
Store at -80°C
Spedito in
Dry ice packs + Cold packs
Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.
Grado
Moligand™
Tipo di azione
ANTAGONIST
Meccanismo d'azione
Antagonist of H 2 receptor
Nomi e identificatori
Pubchem Sid528776388
Sorrisi canoniciCNC(=C[N+](=O)[O-])NCCSCC1=CC=C(O1)CN(C)C
IUPAC Name(E)-1-N'-[2-[[5-[(dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethyl]-1-N-methyl-2-nitroethene-1,1-diamine
InChIKeyVMXUWOKSQNHOCA-UKTHLTGXSA-N
INCHI1S/C13H22N4O3S/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3/h4-5,9,14-15H,6-8,10H2,1-3H3/b13-9+
Isomeri SMILES CN/C(=C\[N+](=O)[O-])/NCCSCC1=CC=C(O1)CN(C)C
PubChem CID 3001055
Peso molecolare 314.39

Documentazione

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic nitrogen compounds
ClasseOrganonitrogen compounds
SubclassAmines
Intermediate Tree Nodes Not available
Direct ParentAralkylamines
Alternative Parents Heteroaromatic compounds  Furans  Trialkylamines  C-nitro compounds  Sulfenyl compounds  Propargyl-type 1,3-dipolar organic compounds  Oxacyclic compounds  Organic oxoazanium compounds  Dialkylthioethers  Dialkylamines  Organopnictogen compounds  Organooxygen compounds  Organic zwitterions  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Aralkylamine - Furan - Heteroaromatic compound - C-nitro compound - Tertiary amine - Tertiary aliphatic amine - Organic nitro compound - Secondary aliphatic amine - Organic oxoazanium - Secondary amine - Thioether - Sulfenyl compound - Allyl-type 1,3-dipolar organic compound - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Oxacycle - Organoheterocyclic compound - Dialkylthioether - Organic zwitterion - Organooxygen compound - Organosulfur compound - Organic oxygen compound - Organic oxide - Organopnictogen compound - Hydrocarbon derivative - Aromatic heteromonocyclic compound
DescrizioneThis compound belongs to the class of organic compounds known as aralkylamines. These are alkylamines in which the alkyl group is substituted at one carbon atom by an aromatic hydrocarbyl group.
External Descriptors C-nitro compound - tertiary amino compound - furans
Struttura 3D
Modello di struttura chimica interattiva





Obiettivi associati (umani)
HRH2 Tclin Histamine H2 receptor (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HRH2 Tclin Histamine H2 receptor (5428 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Homo sapiens (32628 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Caco-2 (12174 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC22A1 Tchem Solute carrier family 22 member 1 (646 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ABCB11 Tchem Bile salt export pump (2311 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC22A2 Tchem Solute carrier family 22 member 2 (261 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Obiettivi associati (non umani)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Meccanismi d'azione
Certificati (CoA, COO, BSE/TSE e tabella di analisi)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot NumberCertificate TypeDataOggetto
I2221006Certificate of AnalysisMay 11, 2026 R425343
Proprietà chimiche e fisiche
SensibilitàMoisture sensitive
Punto di ebollizione (°C)437.1ºC
Punto di fusione (°C)69-70°C
Peso molecolare314.410 g/mol
XLogP30.300
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count9
Exact Mass314.141 Da
Monoisotopic Mass314.141 Da
Topological Polar Surface Area112.000 Ų
Heavy Atom Count21
Formal Charge0
Complexity347.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds1
Covalently-Bonded Unit Count1
Domande frequenti e articoli
Citations of This Product
Riferimenti
1. Jianrui Niu, Hua Jia, Minghao Yu, Jinyu Zhu, Junjun Ma, Zhuang He, Weizhang Zhong, Yongjiang Hou, Yankai Guo.  (2023)  Nitrogen-rich penicillin residue biochar for activation of peroxymonosulfate for an efficient degradation of tetracycline and its dual-pathway mechanism.  PROCESS SAFETY AND ENVIRONMENTAL PROTECTION,      [PMID:] [10.1016/j.psep.2023.11.066]
2. Jiezhou Pan, Haotian Liao, Guidong Gong, Yunxiang He, Qin Wang, Lang Qin, Yaoyao Zhang, Hirotaka Ejima, Blaise L. Tardy, Joseph J. Richardson, Jiaojiao Shang, Orlando J. Rojas, Yong Zeng, Junling Guo.  (2023)  Supramolecular nanoarchitectonics of phenolic-based nanofiller for controlled diffusion of versatile drugs in hydrogels.  JOURNAL OF CONTROLLED RELEASE,      [PMID:37422124] [10.1016/j.jconrel.2023.07.003]
3. Li Chen, Tahir Maqbool, Ghazanfar Nazir, Congyu Hou, Yanna Xu, Yulong Yang, Xihui Zhang.  (2022)  Peroxymonosulfate activated by composite ceramic membrane for the removal of pharmaceuticals and personal care products (PPCPs) mixture: Insights of catalytic and noncatalytic oxidation.  WATER RESEARCH,      [PMID:36470049] [10.1016/j.watres.2022.119444]
4. Lin Wang, Qiya Sun, Yicheng Dou, Zhipeng Zhang, Tingting Yan, Yongmei Li.  (2021)  Fabricating a novel ternary recyclable Fe3O4/graphene/sulfur-doped g-C3N4 composite catalyst for enhanced removal of ranitidine under visible-light irradiation and reducing of its N-nitrosodimethylamine formation potential.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:33588334] [10.1016/j.jhazmat.2021.125288]
5. Yan Xu, Weitao Yang, Zhuoyao Wu, Hui Wang, Tianming Cui, Weiwei Zeng, Yanjing Yun, Bingbo Zhang.  (2024)  A Chromium-Based magnetic resonance probe for in situ gastric pH imaging.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2024.154269]
6. Guodong Shan, Xiuqin Fan, Qingcheng Wang, Li Zhang, Lijun Ge, Weibo Lu, Jing Xue, Kang Chen, Zejun Wang, Qing Shen.  (2025)  Development of a Captiva EMR-lipid clean-up and LC-MS/MS methodology for detecting H2 receptor antagonists in functional foods and food-medicine homology materials.  Applied Food Research,      [PMID:] [10.1016/j.afres.2025.100772]
7. Yun-fei Zhang, Xin Quan, Sheng-gui Chen, Jian-hui Xu, Dan Li, Lei Li, Si-hao Lv, Jin-ze Li, Yi-hang Zhang, Zhuo-wei Zhong.  (2024)  Efficient ranitidine removal using Si3N4-ZVI/PAA system: Mechanistic insights and environmental implications.  Journal of Water Process Engineering,      [PMID:] [10.1016/j.jwpe.2024.106641]
8. Shi Zhengzheng, Li Jia, Pan Yupeng, Li Xuewei, Zhuang Zile, Li Yihan, Zhang Zheng, Wang Zirui, Luo Qizhi, Chen Xuncai.  (2025)  Fe-MOF nanoparticles supported with carbon-defective g-C3N4 nanosheet as visible-light driven photo-Fenton catalyst for efficient degradation of tetracycline hydrochloride.  Emergent Materials,      [PMID:] [10.1007/s42247-025-01071-2]
9. Fazal Muhammad Khoso, Jin-Gang Yu.  (2025)  Selective removal of Cd2+ from aqueous solution using a novel Ranitidine functionalized three-dimensional graphene oxide (3D RN-GO) composite: Kinetics, isotherms, thermodynamics, and regeneration studies.  INORGANIC CHEMISTRY COMMUNICATIONS,      [PMID:] [10.1016/j.inoche.2025.114260]
10. Cheng Shu, Ziqi Cai, Zhenghua Zhang.  (2025)  Symmetric dual-cathode sandwich system for enhanced peroxymonosulfate electrochemical activation and stable water decontamination: performance and mechanism.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2025.134302]
11. Jianhui Xu, Zhijie Cui, Xin Fu, Dan Li, Yanyan Zeng, Yunfei Zhang, Peng Liu, Xiangteng Mo, Kexin Cao, Zijie Shen, Shangkun Ye.  (2025)  Electrocatalytic oxidation of ranitidine using a fluorinated blue titanium dioxide nanotube array electrode.  Journal of Environmental Chemical Engineering,      [PMID:] [10.1016/j.jece.2025.119081]
12. Kun Peng, Qiqin Wang, Weijia Chen, Donghai Xia, Zhengyin Zhou, Yuqiang Wang, Zhengjin Jiang, Fuhai Wu.  (2016)  Phosphatidic acid-functionalized monolithic stationary phase for reversed-phase/cation-exchange mixed mode chromatography.  RSC Advances,  (103): (100891-100898).  [PMID:] [10.1039/C6RA21504A]
13. Yuzhe Wang, Lu sheng, Lin Bu, Huijuan Li, Jianxin Wu, Qing Huang.  (2026)  A novel epidermal mimicking phospholipid vesicle-based permeation assay: EpiPVPA for in vitro permeation evaluation.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,      [PMID:41558553] [10.1016/j.ijpharm.2026.126595]
14. Yizhe Ding, Jiacheng Shi, Yuqian Lin, Qiya Sun, Yuxiang Zhao, Xi Wang, Qian Ping, Lin Wang, Yongmei Li.  (2026)  Unraveling the ranitidine removal mechanism in a novel riboflavin-mediated ultraviolet/peracetic acid system: An integrated density functional theory-machine learning framework.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:41764793] [10.1016/j.jhazmat.2026.141618]
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