RP101988 - ≥98% , CAS No.R658962

CAS: R658962 Cat. No.: R658962 Molecular Weight: 418.45

GRADE & PURITY ≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

RP101988, the major active metabolite of Ozanimod, is a selective, potent S1PR1 (sphingosine-1-phosphate receptor 1) agonist, with EC 50 s of 0.19 nM and 32.8 nM for S1PR1 and S1PR5 , respectivlely.

Appearance:Solid

IC50& Target:S1PR1 0.19 nM (EC 50 ) S1PR5 32.8 nM (EC 50 )

In Vitro:RP101988 is a substrate of P-gp and breast cancer resistance protein (BCRP) drug transporters. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Biological Activity:RP101988, the major active metabolite of Ozanimod, is a selective, potent S1PR1 (sphingosine-1-phosphate receptor 1) agonist, with EC 50 s of 0.19 nM and 32.8 nM for S1PR1 and S1PR5 , respectivlely.

Specifications

Specifications & Purity

≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Names and Identifiers

• Canonical Smiles: O=C(O)CN[C@H]1CCC2=C1C=CC=C2C3=NOC(C4=CC=C(OC(C)C)C(C#N)=C4)=N3
• Molecular Weight: 418.45

Chemical and Physical Properties

• Solubility: DMSO : 125 mg/mL (298.72 mM; Need ultrasonic)