RSV-IN-1 - 10mM in DMSO , CAS No.861139-16-4

CAS: 861139-16-4 Cat. No.: R655311 Formula: C₂₀H₂₁N₅O₄S Peso molecolare: 427.48 PubChem CID: 3943763

QUALITÀ & PUREZZA 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

RSV-IN-1 is a human respiratory syncytical virus (hRSV) inhibitor, with an IC 50 of 0.11 μM.

In Vitro

The concentration of P13 that reduces the number of RSV plaques in HEp-2 cells by 50% (IC 50 ) is 0.11 μM. The concentration of P13 that reduces the viability of HEp-2 by 50% (CC 50 ) is 310 μM. Note that some cytotoxicity of P13 observed at 500 μM might be due to DMSO solvent. Hence, the selective index (CC 50 /IC 50 ) values is 2818 for P13. Note that even at the relatively high concentrations P13 does not completely block the development of RSV plaques. These escape plaques are of smaller size and of non-syncytial phenotype as compared to plaques formed in the absence of inhibitor. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:IC50: 0.11μM (hRSV)

Specifiche

Specifiche e purezza

10mM in DMSO

Meccanismi biochimici e fisiologici

RSV-IN-1 is a human respiratory syncytical virus (hRSV) inhibitor, with an IC 50 of 0.11 μM.

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Nomi e identificatori

Isomeri SMILES

CC1=NN2C(=NN=C2C3=C(C=CC(=C3)S(=O)(=O)N(C)CCO)OC)C4=CC=CC=C14

PubChem CID

3943763

Termini MeSH

N-(2-hydroxyethyl)-4-methoxy-N-methyl-3-(6-methyl(1,2,4)triazolo(3,4-a)phthalazin-3-yl)benzenesulfonamide;N-HMMMTPB cpd

Peso molecolare

427.48