Salicin - Moligand™, 10mM in DMSO , Agonist of TAS2R16, CAS No.138-52-3, Agonist of TAS2R16

CAS: 138-52-3 Cat. No.: S408989 Formula: C₁₃H₁₈O₇ Peso molecolare: 286.28 Beilstein Registry Number: 89593 Numero EC: 205-331-6 PubChem CID: 439503

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

Salicoside,Salicine | β-D-Glucopyranoside, 2-(hydroxymethyl)phenyl

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

Information

Salicin (Salicoside, Salicine) is a phenol β-glycosid produced from willow bark that shows anti-inflammatory effects. It is a natural, non-selectiveCOX-1andCOX-2inhibitor.
In vitro

Salicin (Salicoside, Salicine) is a phenol β-glycosid produced from willow bark that shows anti-inflammatory effects. Salicin is a prodrug which is gradually transported to the lower part of the intestine, hydrolyzed to saligenin by intestinal bacteria, and converted to salicylic acid after absorption. It thus produces an antipyretic action without causing gastric injury.

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥98%

Specifications

Sinonimi

Salicoside,Salicine | β-D-Glucopyranoside, 2-(hydroxymethyl)phenyl

Specifiche e purezza

Moligand™, 10mM in DMSO

Meccanismi biochimici e fisiologici

Salicin (Salicoside, Salicine) is a phenol β-glycosid produced from willow bark that shows anti-inflammatory effects. It is a natural, non-selective COX-1 and COX-2 inhibitor.

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Grado

Moligand™

Tipo di azione

AGONIST

Meccanismo d'azione

Agonist of TAS2R16

Nomi e identificatori

• Isomeri SMILES: C1=CC=C(C(=C1)CO)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O
• WGK Germania: 3
• RTECS: LZ5901700
• CAS alternativo: 138-52-3
• PubChem CID: 439503
• Numero NSC: 758201
• Termini MeSH: salicin;salicyl alcohol glucoside
• Peso molecolare: 286.28
• Beilstein: 89593
• Reaxy-Rn: 89593

Obiettivi associati (umani)

TAS2R16 Tchem Taste receptor type 2 member 16 (0 Activities)

Discover Target: TAS2R16

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Proprietà chimiche e fisiche

• Solubilità: Solubility (25°C) In vitro DMSO: 41 mg/mL (197.79 mM); Ethanol: 41 mg/mL (197.79 mM); Water: Insoluble
• Rotazione specifica [α]: -62 ° (C=3, H2O)
• Punto di fusione (°C): 199-202°C

Riferimenti

1. Lei Chen, Ning Li, Min-Hua Zong.  (2011)  A glucose-tolerant β-glucosidase from Prunus domestica seeds: Purification and characterization.  PROCESS BIOCHEMISTRY,      [PMID:] [10.1016/j.procbio.2011.10.023]

2. Zhenyue Wang, Faidah Arina Nur, Jingyi Ma, Jianguo Wang, Chuanwang Cao.  (2019)  Effects of poplar secondary metabolites on performance and detoxification enzyme activity of Lymantria dispar.  COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY,      [PMID:31401083] [10.1016/j.cbpc.2019.108587]

3. Xinqi Gao, Yafang Lei, Teng Sun, Yuanze Ma, Hao Guan, Li Yan.  (2025)  Evaluation of Anti-Fungal Activities of Environmentally Friendly Wood Preservative from Thermal-Induced Lignified Twigs.  Forests,  16  (1): (119).  [PMID:] [10.3390/f16010119]

4. Shangguang Du, Hao Wan, Jun Luo, Xiaohua Duan, Zhengrong Zou.  (2024)  Metabolic profiling of Citrus maxima L. seedlings in response to cadmium stress using UPLC-QTOF-MS.  PLANT PHYSIOLOGY AND BIOCHEMISTRY,      [PMID:38996714] [10.1016/j.plaphy.2024.108920]

5. Mingzhen Zhang, Cong Liu, Yan Zhang, Zhangyaoyu Yuan, Shi Chen, Huihui Zhang, Xianju Huang, Lvyi Chen, Zhinan Mei, Yuebin Ge.  (2025)  Bioactive Components, Untargeted Metabolomics and Bioinformatics of Chaenomeles speciosa Fruit on Uric Acid-Lowering Activity Assessment.  Foods,  15  (1): (20).  [PMID:41517086] [10.3390/foods15010020]