GRADE & PURITYMoligand™?Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.10mM in DMSO
Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Panoramica
Information
SB-3CT SB-3CT is an effective and selective gelatinase inhibitor with K i of 13.9 nM and 600 nM for MMP-2 and MMP-9 , respectively. In vitro
SB-3CT directly inhibits bone marrow endothelial cell invasion and tubule formation in Matrigel in vitro.
In vivo
In L-CI.5s T-cell lymphoma model, SB-3CT (5-50 mg/kg/d i.p.) potently inhibit liver metastasis and increases survival of mice. SB-3CT (50 mg/kg/d i.p.) inhibits human prostate cancer growth, osteolysis and angiogenesis in a bone metastasis model. In a mouse model of embolus-induced “permanent” focal cerebral ischemia, SB-3CT counteracts degradation of neuronal laminin, protects neurons from ischemic cell death, and ameliorates neurobehavioral outcomes after embolic MCA occlusion. Cell Data
cell lines：A10 cells (Vascular SMC)
Concentrations：
Incubation Time：
Powder Purity:≥97%
Specifications
Sinonimi
2-[[(4-phenoxyphenyl)sulfonyl]methyl]-thiirane
Specifiche e purezza
Moligand™, 10mM in DMSO
Meccanismi biochimici e fisiologici
SB-3CT is an effective and selective gelatinase inhibitor with Ki of 13.9 nM and 600 nM for MMP-2 and MMP-9, respectively.
Condizioni di conservazione di stoccaggio
Store at -80°C
Spedito in
Dry ice packs + Cold packs
Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.
Grado
Moligand™
Tipo di azione
INHIBITOR
Meccanismo d'azione
Inhibitor of MMP2;Inhibitor of MMP9
Nomi e identificatori
Isomeri SMILES
C1C(S1)CS(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3
PubChem CID
9883002
Peso molecolare
306.4
Documentazione
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
1.Xiao-lei ZHANG, Meng-ni HU, Ya-nan LI, Yao WANG, Zhen RONG, Jun MA. (2025) Effect of electroacupuncture on MMP-2/9 pathway mediated the blood-brain barrier permeability in mice with Parkinson's disease. World Journal of Acupuncture-Moxibustion, [PMID:][10.1016/j.wjam.2025.01.002]
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