SB-633825 - 10mM in DMSO , CAS No.956613-01-7

CAS: 956613-01-7 Cat. No.: S655218 Formula: C₂₈H₂₅N₃O₃S Peso molecolare: 483.58 PubChem CID: 44433173

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

SB-633825 is a potent and ATP-competitive inhibitor of TIE2 , LOK (STK10) and BRK with IC 50 s of 3.5 nM, 66 nM, 150 nM, respectively. SB-633825 can inhibit cancer cell growth and angiogenesis

In Vitro

SB-633825 inhibits TIE2 Tyrosine-protein kinase (TIE2), lymphocyte-oriented kinase (LOK; STK10) and breast tumor kinase (Brk; PTK6). SB-633825 inhibits LOK to 44% maximal activity and TIE2 to 75% maximal activity at 0.1 µM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:Tie2 3.5 nM (IC 50 )

Specifications

Specifiche e purezza

10mM in DMSO

Meccanismi biochimici e fisiologici

SB-633825 is a potent and ATP-competitive inhibitor of TIE2 , LOK (STK10) and BRK with IC 50 s of 3.5 nM, 66 nM, 150 nM, respectively. SB-633825 can inhibit cancer cell growth and angiogenesis.

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Nomi e identificatori

• Isomeri SMILES: CC1=C(C=CC(=C1)S(=O)(=O)C)C2=NC(=C(N2C)C3=CC4=C(C=C3)C=C(C=C4)OC)C5=CC=NC=C5
• PubChem CID: 44433173
• Peso molecolare: 483.58