SC99 - ≥98% , CAS No.882290-02-0

CAS: 882290-02-0 Cat. No.: S412698 Formula: C₁₅H₈Cl₂FN₃O Peso molecolare: 336.15 PubChem CID: 5896323

QUALITÀ & PUREZZA ≥98%

Synonyms

N'-(3-Chloro-4-fluorophenyl)-2-(4-chlorophenyl)-2-oxoacetohydrazonoyl cyanide

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Panoramica

Information

SC99 is an orally active, selective inhibitor of STAT3 that docks into the ATP-binding pocket of JAK2 and inhibits phosphorylation of JAK2 and STAT3. SC99 inhibits platelet activation, aggregation and displays potent anti-myeloma, anti-thrombotic activities.

Specifiche

Sinonimi

N'-(3-Chloro-4-fluorophenyl)-2-(4-chlorophenyl)-2-oxoacetohydrazonoyl cyanide

Specifiche e purezza

≥98%

Meccanismi biochimici e fisiologici

SC99 is an orally active, selective inhibitor of STAT3 that docks into the ATP-binding pocket of JAK2 and inhibits phosphorylation of JAK2 and STAT3. SC99 inhibits platelet activation, aggregation and displays potent anti-myeloma, anti-thrombotic activiti

Condizioni di conservazione di stoccaggio

Protected from light,Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Tipo di azione

ACTIVATOR

Purezza

≥98%

Nomi e identificatori

Pubchem Sid

528767066

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/528767066

Sorrisi canonici

C1=CC(=CC=C1C(=O)C(=NNC2=CC(=C(C=C2)F)Cl)C#N)Cl

IUPAC Name

(1E)-N-(3-chloro-4-fluoroanilino)-2-(4-chlorophenyl)-2-oxoethanimidoyl cyanide

InChIKey

ZKULFSMYRSFHKE-KGENOOAVSA-N

INCHI

1S/C15H8Cl2FN3O/c16-10-3-1-9(2-4-10)15(22)14(8-19)21-20-11-5-6-13(18)12(17)7-11/h1-7,20H/b21-14+

Isomeri SMILES

C1=CC(=CC=C1C(=O)/C(=N/NC2=CC(=C(C=C2)F)Cl)/C#N)Cl

PubChem CID

5896323

Peso molecolare

336.15

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Benzene and substituted derivatives
      • Subclass Phenylhydrazines

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Benzene and substituted derivatives
• Subclass: Phenylhydrazines
• Intermediate Tree Nodes: Not available
• Direct Parent: Phenylhydrazines
• Alternative Parents: Benzoyl derivatives Aryl ketones Fluorobenzenes Chlorobenzenes Aryl fluorides Aryl chlorides Nitriles Hydrazones Organopnictogen compounds Organofluorides Organochlorides Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Benzoyl - Phenylhydrazine - Aryl ketone - Chlorobenzene - Fluorobenzene - Halobenzene - Aryl halide - Aryl chloride - Aryl fluoride - Ketone - Hydrazone - Carbonitrile - Nitrile - Organic oxide - Organohalogen compound - Organochloride - Organofluoride - Organonitrogen compound - Organooxygen compound - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Aromatic homomonocyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as phenylhydrazines. These are compounds containing a phenylhydrazide moiety, which consists of a hydrazide substituent attached to a phenyl group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Obiettivi associati (non umani)

Plasmodium berghei (192651 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Meccanismi d'azione

Proprietà chimiche e fisiche

• Sensibilità: Light sensitive