Schizandrol A - ≥98% , CAS No.7432-28-2

CAS: 7432-28-2 Cat. No.: S1522825 Formula: C₂₄H₃₂O₇ Peso molecolare: 432.51 Numero EC: 694-563-5 PubChem CID: 23915

GRADE & PURITY ≥98%

Storage

Room temperature

Shipped In

Normal

Panoramica

Schizandrin may be used in oxidative stress-related cell signaling studies.

Specifications

Specifiche e purezza

≥98%

Meccanismi biochimici e fisiologici

Schizandrin is a natural product with several biological properties involved with antioxidant and anti-inflammatory activities. It reduces the formation of ROS, inhibits the mitochondrial pathway of the apoptotic process and oxidative stress. Schizandrin

Condizioni di conservazione di stoccaggio

Room temperature

Spedito in

Normal

Purezza

≥98%

Nomi e identificatori

• Sorrisi canonici: CC1CC2=CC(=C(C(=C2C3=C(C(=C(C=C3CC1(C)O)OC)OC)OC)OC)OC)OC
• IUPAC Name: 3,4,5,14,15,16-hexamethoxy-9,10-dimethyltricyclo[10.4.0.02,7]hexadeca-1(16),2,4,6,12,14-hexaen-9-ol
• InChIKey: YEFOAORQXAOVJQ-UHFFFAOYSA-N
• INCHI: 1S/C24H32O7/c1-13-9-14-10-16(26-3)20(28-5)22(30-7)18(14)19-15(12-24(13,2)25)11-17(27-4)21(29-6)23(19)31-8/h10-11,13,25H,9,12H2,1-8H3
• Isomeri SMILES: CC1CC2=CC(=C(C(=C2C3=C(C(=C(C=C3CC1(C)O)OC)OC)OC)OC)OC)OC
• WGK Germania: 3
• PubChem CID: 23915
• Peso molecolare: 432.51

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Phenylpropanoids and polyketides
    • Classe Tannins
      • Subclass Hydrolyzable tannins

• Kingdom: Organic compounds
• Superclass: Phenylpropanoids and polyketides
• Classe: Tannins
• Subclass: Hydrolyzable tannins
• Intermediate Tree Nodes: Not available
• Direct Parent: Hydrolyzable tannins
• Alternative Parents: Dibenzocyclooctadiene lignans Anisoles Alkyl aryl ethers Tertiary alcohols Hydrocarbon derivatives
• Molecular Framework: Aromatic homopolycyclic compounds
• Substituents: Hydrolyzable tannin - Dibenzocyclooctane lignan - Anisole - Alkyl aryl ether - Benzenoid - Tertiary alcohol - Ether - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Alcohol - Aromatic homopolycyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as hydrolyzable tannins. These are tannins with a structure characterized by either of the following models. In model 1, the structure contains galloyl units (in some cases, shikimic acid units) that are linked to diverse polyol carbohydrate-, catechin-, or triterpenoid units. In model 2, contains at least two galloyl units C-C coupled to each other, and do not contain a glycosidically linked catechin unit.
• External Descriptors: tannin

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Proprietà chimiche e fisiche

• Rotazione specifica [α]: 75 to 95°, c = 1 in methanol
• Peso molecolare: 432.500 g/mol
• XLogP3: 4.000
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 6
• Exact Mass: 432.215 Da
• Monoisotopic Mass: 432.215 Da
• Topological Polar Surface Area: 75.600 Ų
• Heavy Atom Count: 31
• Formal Charge: 0
• Complexity: 574.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 2
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Riferimenti

1. Jincai Wang, Xiaoling Huang, Jie Mei, Xinwei Chen, Rong Ma, Guowei Li, Zhengjin Jiang, Jialiang Guo.  (2023)  Screening of trypsin inhibitors in Cotinus coggygria Scop. extract using at-line nanofractionation coupled with semi-preparative reverse-phase liquid chromatography.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:36738572] [10.1016/j.chroma.2023.463817]

2. Jingyi Jian, Jiaming Yuan, Yu Fan, Jincai Wang, Tingting Zhang, Jeroen Kool, Zhengjin Jiang.  (2022)  High-Resolution Bioassay Profiling with Complemented Sensitivity and Resolution for Pancreatic Lipase Inhibitor Screening.  MOLECULES,  27  (20): (6923).  [PMID:36296516] [10.3390/molecules27206923]

3. Xiao-Hua Zhang, Hai-Long Wu, Xiao-Li Yin, Yong Li, Xiang-Dong Qing, Hui-Wen Gu, Chao Kang, Ru-Qin Yu.  (2016)  Exploiting third-order advantage using four-way calibration method for direct quantitative analysis of active ingredients of Schisandra chinensis in DMEM by processing four-way excitation–emission-solvent fluorescence data.  CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS,      [PMID:] [10.1016/j.chemolab.2016.04.008]

4. Zhang Jinpeng, Cui Xinyuan, Zhao Shuo, Chang Zenghui, Zhang Junshuo, Chen Yufeng, Liu Jiale, Sun Guohao, Wang Yiyuan, Liu Yuanyuan.  (2024)  Establishment of a pharmacokinetics and pharmacodynamics model of Schisandra lignans against hippocampal neurotransmitters in AD rats based on microdi-alysis liquid chromatography-mass spectrometry.  Frontiers in Pharmacology,      [PMID:38529184] [10.3389/fphar.2024.1342121]

5. Yu Fan, Jincai Wang, Jingyi Jian, Yalei Wen, Jiahao Li, Hao Tian, Jacques Crommen, Wei Bi, Tingting Zhang, Zhengjin Jiang.  (2024)  High-throughput discovery of highly selective reversible hMAO-B inhibitors based on at-line nanofractionation.  Acta Pharmaceutica Sinica B,      [PMID:38572096] [10.1016/j.apsb.2024.01.020]

6. Jiaming YUAN, Zhuoping ZHENG, Zhongkang WANG, Hao TIAN, Lingling XI, Jacques CROMMEN, Tingting ZHANG, Jincai WANG, Zhengjin JIANG.  (2025)  Integrating High-resolution Bioassay Profiling with Affinity-based Ligand Fishing for Unveiling Galloylated Derivatives as Novel Catechol-O-methyltransferase Inhibitors in Paeonia lactiflora Pall..  Journal of Pharmaceutical Analysis,      [PMID:41626564] [10.1016/j.jpha.2025.101449]

Domande frequenti

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at room temperature.

How is this product shipped?

This product ships under standard ambient conditions. No temperature-controlled packaging is required.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 7432-28-2, the molecular formula is C24H32O7, and the molecular weight is 432.51 g/mol. InChIKey YEFOAORQXAOVJQ-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.