SDZ 224-015 - ≥95% , CAS No.161511-45-1

CAS: 161511-45-1 Cat. No.: S646873 Formula: C₃₀H₃₅Cl₂N₃O₉ Peso molecolare: 652.52

GRADE & PURITY ≥95%

Storage

Protected from light,Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Panoramica

SDZ 224-015 is an orally active inhibitor of the interleukin-1 beta (IL-1β) converting enzyme and caspase-1. SDZ 224-015 possesses anti-COVID-19 activity, targeting M pro (IC 50 of 30 nM).

In Vivo

SDZ 224-015 (0.3-300 μg/kg) potently reduces carrageenin-induced paw oedema. SDZ 224-015 (0.2-5 mg/kg, p.o.) displays analgesic activity in the Randall-Selitto yeast-inflamed paw pressure test, significant at a dose of 1 mg/kg. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Specifications

Specifiche e purezza

≥95%

Meccanismi biochimici e fisiologici

SDZ 224-015 is an orally active inhibitor of the interleukin-1 beta (IL-1β) converting enzyme and caspase-1 . SDZ 224-015 possesses anti-COVID-19 activity, targeting M pro (IC 50 of 30 nM).

Condizioni di conservazione di stoccaggio

Protected from light,Store at -20°C,Desiccated

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Purezza

≥95%

Nomi e identificatori

Sorrisi canonici

O=C(OCC1=CC=CC=C1)N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](CC(OCC)=O)C(COC(C2=C(C=CC=C2Cl)Cl)=O)=O)=O)=O

Peso molecolare

652.52

Proprietà chimiche e fisiche

• Solubilità: DMSO : 100 mg/mL (153.25 mM; Need ultrasonic)