sericin, CAS No.60650-88-6

CAS: 60650-88-6 Cat. No.: S488097

Panoramica

Sericin is a protein derived from the silkworm cocoon and has a number of beneficial characteristics for culturing mammalian cells. It has cryoprotective properties that allow for replacement of FBS in cryopreservation media. 1% sericin (w/v) along with 0.5% (w/v) maltose, 0.3% (w/v) proline, 0.3% (w/v) glutamine and 10% DMSO is comparable to 90% FBS and 10% DMSO. Furthermore, sericin can act as a FBS replacement in cell culture and stimulate cell growth and in certain situations, inhibit cell death.

Application characteristics:

(1) Serine and aspartic acid and other polar side amino acids in sericin are extremely high. It is a protein with abundant hydrophilic groups. Because the amino acids with hydrophilic polarity in sericin account for about 75%, especially serine, which accounts for nearly 30%, has 50 times stronger hygroscopicity than glycerin, sericin as a cosmetic raw material and chemical fiber coating raw material has excellent hygroscopic, moisturizing, breathable and antimicrobial functions.

(2) the film forming property of the sericin on the hair is excellent, the film has luster, and the hair has good hand feeling and elasticity. It can not only avoid the damage of hair caused by direct contact with chemicals, but also increase the elasticity and luster of hair. Sericin forms a film with a certain strength on the surface of hair, which can be used as hair styling agent. 

(3) Sericin has excellent oxidation resistance. Can effectively inhibit that activity of polyphenol oxidase in food, is an excellent natural antioxidant for grease food, and has a very significant value for developing an additive for prolon the preservation period of dairy foods. 

(4) the sericin protein is used as a main raw material, is crosslinked by a crosslinking agent, and is coated on products such as chemical fibers, underwear, bedding, skin-friendly products, leather and the like, so that the sericin protein has the real silk effects of skin care, skin-friendliness, antibiosis, comfort and the like.

Specifications

Product Name

sericin, CAS No.60650-88-6

Meccanismi biochimici e fisiologici

Sericin is used as an adhesive to maintain the integrity of the cocoon structure. The strong polar side chain groups of Sericin will affect its physical and biological properties. Studies have shown that Sericin has a variety of biological functions, such

CAS

60650-88-6

Tipo di molecola

Proteine

Stoccaggio e spedizione

Condizioni di conservazione di stoccaggio

Room temperature

Riferimenti

1. Ting Wu, Haiying Liu, Hongcai Wang, Yanan Bu, Jiayi Liu, Xiuqiong Chen, Huiqiong Yan, Qiang Lin.  (2023)  Fabrication of alginate/sericin/cellulose nanocrystals interpenetrating network composite hydrogels with enhanced physicochemical properties and biological activity.  JOURNAL OF APPLIED POLYMER SCIENCE,      [PMID:] [10.1002/app.55052]

2. Tianyue Zhao, Ran Wang, Shengnan Wei, Lexin Zhang, Zhiwei Liu, Mingli Wang, Tifeng Jiao.  (2024)  Preparation of Langmuir-Blodgett composite films based on sericin protein and silk fibroin with good surface-enhanced Raman scattering and photovoltaic properties.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2024.133669]

3. Tongtong Xu, Ang Li, Xudong Zheng, Biao Ji, Jinfeng Mei, Man Zhou, Zhongyu Li.  (2023)  Porous carboxymethyl cellulose nanocrystalline imprinted composite aerogels for selective adsorption of gadolinium.  CHEMOSPHERE,      [PMID:38096994] [10.1016/j.chemosphere.2023.140931]

4. Ming-Liang Wu, Jin-Feng Li, Xiao-Li Ku, Yi-Dong Li, Jian-Bing Zeng.  (2025)  Mechanically Robust and Room-Temperature Self-Healing Biobased Conductive Elastomers with Polydopamine-Functionalized Segregated Structure.  MACROMOLECULES,      [PMID:] [10.1021/acs.macromol.5c01844]

5. Muhammad Saqib, Wen-Xin Chen, Yun Lei, Ai-Lin Liu.  (2025)  Sericin as a New Coreactant for Lucigenin Chemiluminescence: A Novel System for the Ultrasensitive Detection of Sericin and Superoxide Dismutase.  ANALYTICAL CHEMISTRY,      [PMID:41147793] [10.1021/acs.analchem.5c04780]

6. Lulu Zhang, Haiyang Liu, Jin Ren, Junyi Shao, Yanrong Cao, Shuangshuang Wang, Changchun Peng, Shengwen Shao, Haixia Ge, Jingmou Yu.  (2025)  Reduction-Responsive Nanoparticles Self-Assembled from Sericin-ss-Doxorubicin Conjugate for Hydrophobic IR780 Delivery with Integration of Antitumor Chemo-Phototherapy.  International Journal of Nanomedicine,      [PMID:41244890] [10.2147/IJN.S553474]

7. Kaifeng Gu, Yingdong Chen, Qi He, Yong Zhou.  (2025)  A Simple Process for Controlling the Separation Layer Structure of Nanofiltration Composite Membrane Assisted by Sericin.  JOURNAL OF APPLIED POLYMER SCIENCE,      [PMID:] [10.1002/app.70057]

8. Yang Yuan, Jiawei Zhang, Fangzheng Yu, Chen Wang, Jiale He, Zheng Zhao.  (2026)  Multifunctional Poly(thioctic acid) Composite Hydrogels with Self-Healing, Antibacterial, Antioxidant, and Adhesive Properties.  Materials,  19  (13): (2695).  [PMID:42451777] [10.3390/ma19132695]

9. Ziwei Li, Qiuying Wu, Rui Ni, Jingjing Wang, Meiyang Yang, Wenyuan Zhang, Jiaming Li, Dan Peng, Lin Song, Yao Liu.  (2026)  A multifunctional hydrogel co-encapsulating ROS-responsive quercetin nanoparticles and ADSCs to accelerate infected wound healing.  MATERIALS & DESIGN,      [PMID:] [10.1016/j.matdes.2026.116680]

10. Wei Liu, Lin Wang, Kunyi Wang, Xinzhi Liang, Ting Liu, Jingxuan Tan, Xiaoyong Qiu, Jingcheng Hao.  (2026)  Double-layer electrospun fibers with integrated gas-selective and bioactive functions for the preservation of perishable fruit.  FOOD RESEARCH INTERNATIONAL,      [PMID:] [10.1016/j.foodres.2026.119931]