SHP389 - 10mM in DMSO , CAS No.2235394-90-6

CAS: 2235394-90-6 Cat. No.: S656326 Formula: C₂₃H₂₉ClN₈O₂ Peso molecolare: 484.98 PubChem CID: 124147932

QUALITÀ & PUREZZA 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

SHP389 is an allosteric SHP2 inhibitor, with an IC 50 of 36 nM for both SHP2 and p-ERK

In Vivo

SHP389 modulates MAPK signaling in vivo . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:IC50: 36 nM (SHP2 and p-ERK)

Specifiche

Specifiche e purezza

10mM in DMSO

Meccanismi biochimici e fisiologici

SHP389 is an allosteric SHP2 inhibitor, with an IC 50 of 36 nM for both SHP2 and p-ERK.

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Nomi e identificatori

Isomeri SMILES

C[C@H]1[C@H](C2(CCN(CC2)C3=NC4=NNC(=C4C(=O)N3C)C5=C(C(=NC=C5)NC6CC6)Cl)CO1)N

PubChem CID

124147932

Peso molecolare

484.98

Obiettivi associati (umani)

PTPN11 Tchem Tyrosine-protein phosphatase non-receptor type 11 (2 Activities)

Discover Target: PTPN11

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)