Silybin - Moligand™, 10 mM in DMSO , CAS No.802918-57-6

CAS: 802918-57-6 Cat. No.: S1499820 Formula: C₂₅H₂₂O₁₀ Peso molecolare: 482.44 Numero EC: 806-403-5 PubChem CID: 3086637

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

Silybin is a flavonolignan isolated from milk thistle ( Silybum marianum ) seeds. Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity .

Specifications

Specifiche e purezza

Moligand™, 10 mM in DMSO

Condizioni di conservazione di stoccaggio

Protected from light,Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Grado

Moligand™

Nomi e identificatori

• Isomeri SMILES: COC1=C(C=CC(=C1)C2C(OC3=C(O2)C=C(C=C3)[C@@H]4[C@H](C(=O)C5=C(C=C(C=C5O4)O)O)O)CO)O
• PubChem CID: 3086637
• Peso molecolare: 482.44

Proprietà chimiche e fisiche

• Punto di fusione (°C): 152-153° C

Riferimenti

1. Guanglu Wang, Yue Xin, Kaixin Ping, Xuhui Xu, Ying Sun, Xing Li, Xinying Guan, Jingquan Dong.  (2023)  Silybin mitigates chronic Avermectin exposure-induced intestinal damage and growth inhibition in carp.  ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,      [PMID:38135203] [10.1016/j.etap.2023.104351]

2. Pan En-Zhuang, Xin Yue, Li Xue-Qing, Wu Xin-Yu, Tan Xue-Lian, Dong Jing-Quan.  (2023)  Ameliorative effects of silybin against avermectin-triggered carp spleen mitochondrial dysfunction and apoptosis through inhibition of PERK-ATF4-CHOP signaling pathway.  FISH PHYSIOLOGY AND BIOCHEMISTRY,      [PMID:37542703] [10.1007/s10695-023-01228-y]

3. Qiang-Ming Li, Xiu-Rong Yang, Xue-Qiang Zha, Li-Hua Pan, Dan-Dan Zang, Feng-Yun Zhang, Jian-Ping Luo.  (2022)  Protective Effects of Three Flavonoids from Dendrobium huoshanense Flowers on Alcohol-Induced Hepatocyte Injury via Activating Nrf2 and Inhibiting NF-κB Pathways.  CHEMISTRY & BIODIVERSITY,  19  (8): (e202200471).  [PMID:35774029] [10.1002/cbdv.202200471]

4. Meirong Huo, Honglan Wang, Ying Zhang, Han Cai, Pan Zhang, Lingchao Li, Jianping Zhou, Tingjie Yin.  (2020)  Co-delivery of silybin and paclitaxel by dextran-based nanoparticles for effective anti-tumor treatment through chemotherapy sensitization and microenvironment modulation.  JOURNAL OF CONTROLLED RELEASE,      [PMID:32044390] [10.1016/j.jconrel.2020.02.017]

5. Yong Li, Youdong Zhou, Yinqiu Tan, Gang Deng.  (2025)  Anti-Inflammatory Treatment of Subarachnoid Hemorrhage by Self-Assembled Silymarin Nanoparticles.  Small Science,      [PMID:40657200] [10.1002/smsc.202400322]

Domande frequenti

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C, protected from light. The material is light-sensitive — keep it in its original opaque or amber container.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 802918-57-6, the molecular formula is C25H22O10, and the molecular weight is 482.44 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.