Sinefungin - Moligand™, 10 mM in Water , CAS No.58944-73-3

CAS: 58944-73-3 Cat. No.: S1493491 Formula: C₁₅H₂₃N₇O₅ Peso molecolare: 381.39 Numero EC: 637-385-5 PubChem CID: 65482

GRADE & PURITY Moligand™, 10 mM in Water

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

Sinefungin is a potent inhibitor of virion mRNA (guanine-7-)-methyltransferase, mRNA (nucleoside-2'-)-methyltransferase , and viral multiplication. Sinefungin, a SET7/9 inhibitor, ameliorates renal fibrosis by inhibiting H3K4 methylation.

Specifications

Specifiche e purezza

Moligand™, 10 mM in Water

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Grado

Moligand™

Nomi e identificatori

• Isomeri SMILES: C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)C[C@H](CC[C@@H](C(=O)O)N)N)O)O)N
• WGK Germania: 3
• RTECS: HE3140000
• PubChem CID: 65482
• Peso molecolare: 381.39

Riferimenti

1. Rui-Li Zhu, Ying-Kun Zhi, Lang Yi, Jin-Fang Luo, Jing Li, Sha-Sha Bai, Liang Liu, Pei-Xun Wang, Hua Zhou, Yan Dong.  (2019)  Sinomenine regulates CD14/TLR4, JAK2/STAT3 pathway and calcium signal via α7nAChR to inhibit inflammation in LPS-stimulated macrophages.  IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY,      [PMID:30896303] [10.1080/08923973.2019.1568451]

2. Lang Yi, Yan-jun Lyn, Chong Peng, Rui-li Zhu, Sha-sha Bai, Liang Liu, Pei-xun Wang, Hua Zhou, Yan Dong.  (2018)  Sinomenine inhibits fibroblast-like synoviocyte proliferation by regulating α7nAChR expression via ERK/Egr-1 pathway.  INTERNATIONAL IMMUNOPHARMACOLOGY,      [PMID:29367088] [10.1016/j.intimp.2018.01.015]

3. Biao Zhou, Xiaolong Lu, Zhi Tang, Dan Liu, Youliang Zhou, Peng Zeng, Hui Xiong.  (2017)  Influence of sinomenine upon mesenchymal stem cells in osteoclastogenesis.  BIOMEDICINE & PHARMACOTHERAPY,      [PMID:28437887] [10.1016/j.biopha.2017.03.084]

Domande frequenti

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 58944-73-3, the molecular formula is C15H23N7O5, and the molecular weight is 381.39 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.