SJ10542 is a potent and selective JAK2/3 directing phenyl glutarimide (PG)-PROTAC with DC 50 s of 14, 11, and 24 nM for JAK2 , JAK3 , and JAK2-fusion ALL, respectively. SJ10542 utilizes a PG ligand as the cereblon (CRBN) recruiter.
Biological Activity:SJ10542 is a potent and selective JAK2/3 directing phenyl glutarimide (PG)-PROTAC with DC 50 s of 14, 11, and 24 nM for JAK2 , JAK3 , and JAK2-fusion ALL, respectively. SJ10542 utilizes a PG ligand as the cereblon (CRBN) recruiter.
Specifiche
Specifiche e purezza
≥99%
Condizioni di conservazione di stoccaggio
Store at 2-8°C,Desiccated
Spedito in
Wet ice
Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.
Purezza
≥99%
Nomi e identificatori
Peso molecolare
818.95
Dati avanzati
Certificati (CoA, COO, BSE/TSE e tabella di analisi)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Proprietà chimiche e fisiche
Solubilità
DMSO : 46.67 mg/mL (56.99 mM; Need ultrasonic)
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Recensioni
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Domande frequenti
What is the purity of this product?
This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
How should this product be stored?
Store at 2–8 °C, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.
How is this product shipped?
This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is S658806, the molecular formula is C41H46N12O5S, and the molecular weight is 818.95 g/mol.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
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