SKI-I - ≥90% , CAS No.306301-68-8

CAS: 306301-68-8 Cat. No.: S275155 Molecular Weight: 406.44 EC Number: 999-234-2 PubChem CID: 137269090

GRADE & PURITY ≥90%

Synonyms

5-(2-Naphthalenyl)-1H-pyrazole-3-carboxylicacid2-[(2-hydroxy-1-naphthalenyl)methylene]hydrazide

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Overview

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Specifications

Synonyms

5-(2-Naphthalenyl)-1H-pyrazole-3-carboxylicacid2-[(2-hydroxy-1-naphthalenyl)methylene]hydrazide

Specifications & Purity

≥90%

Biochemical and Physiological Mechanisms

Specific non-lipid sphingosine kinase (SK) inhibitor. Inhibits SK1 and SK2. Inhibits sphingosine 1-phosphate (S1P) production and pro-apoptotic. Induces autophagy. Cell permeable and active in vivo and in vitro .

Storage

Store at -20°C, Desiccated

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Note

Unstable; make up solutions fresh and use immediately. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purity

≥90%

Names and Identifiers

• Canonical Smiles: C1C(NNC1C(=O)NN=CC2=C(C=CC3=CC=CC=C32)O)C4=CC5=CC=CC=C5C=C4
• IUPAC Name: N-[(E)-(2-hydroxynaphthalen-1-yl)methylideneamino]-5-naphthalen-2-ylpyrazolidine-3-carboxamide
• InChIKey: LMCALHGHWCFFHD-CVKSISIWSA-N
• INCHI: 1S/C25H22N4O2/c30-24-12-11-17-6-3-4-8-20(17)21(24)15-26-29-25(31)23-14-22(27-28-23)19-10-9-16-5-1-2-7-18(16)13-19/h1-13,15,22-23,27-28,30H,14H2,(H,29,31)/b26-15+
• PubChem CID: 137269090
• Molecular Weight: 406.44

Chemical and Physical Properties

• Solubility: Soluble in DMSO to 100 mM