GRADE & PURITYMoligand™?Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.≥99%(T)
Moligand™, ≥99%(T) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Room temperature,Argon charged Ships Normal Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 6 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Panoramica
Sodium dichloroacetate is a mitochondrial pyruvate dehydrogenase kinase (PDK) inhibitor that exhibits potent anti-leukemic activity.
Sodium dichloroacetate can be used as an organic salt precursor for synthesizing microporous carbon that is useful in developing carbon-based adsorbents.
Inhibitor of mitochondrial pyruvate dehydrogenase kinase (PDK). Shifts pyruvate metabolism from glycolysis and lactate production to glucose oxidation in the mitochondria. Induces mitochondrial-dependent apoptosis and reverses the inhibition/downregulatio
Alpha-halocarboxylic acid - Carboxylic acid salt - Organic metal halide - Carboxylic acid - Organic alkali metal salt - Monocarboxylic acid or derivatives - Alkyl chloride - Organic salt - Organooxygen compound - Organochloride - Organohalogen compound - Organic sodium salt - Hydrocarbon derivative - Organic oxide - Carbonyl group - Organic oxygen compound - Alkyl halide - Aliphatic acyclic compound
Descrizione
This compound belongs to the class of organic compounds known as alpha-halocarboxylic acids. These are carboxylic acids containing a halogen atom bonded to the alpha carbon atom.
External Descriptors
Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
2.Shengcun Ma, Xiaoqi Guo, Baiyang Chen. (2016) Toward better understanding of chloral hydrate stability in water: Kinetics, pathways, and influencing factors. CHEMOSPHERE, [PMID:27206269][10.1016/j.chemosphere.2016.05.018]
3.Shiyuan Xiao, Yue Li, Jun Wang, Mengran Wang, Bing Bu, Wenmin Jiang. (2025) Lactylated histone H4K8 regulation of MFN2/Wnt signaling integrates glycolytic metabolism and Müller cell activation in the pathogenesis of glaucoma. NEUROBIOLOGY OF DISEASE, [PMID:41197676][10.1016/j.nbd.2025.107178]
4.Xinyu Zhang, Yujie Liu, Ziling Yuan, Haomin Chen, Danyang Ma, Bingzhi Li, Ruihua Liu, Chao Yang. (2025) Metabolic engineering of Pseudomonas putida for mineralization of 1,2-dichloroethane and 2,4-dichlorophenoxyacetic acid and its application in wastewater bioremediation. Journal of Environmental Chemical Engineering, 14 (1):(120844). [PMID:][10.1016/j.jece.2025.120844]
5.Ye Tian, Mengxing Yu, Lei Wang, Xiaohan Zhu, Jiahui Wei, Ningbo Yang, Fengli Yu, Bing Yuan. (2026) Highly dispersed copper on lignin-based nitrogen-doped mesoporous carbon for selective hydrodeoxygenation of vanillin. Journal of Environmental Chemical Engineering, 14 (3):(122304). [PMID:][10.1016/j.jece.2026.122304]
6.Yuchen Qu, Zhuan Yang, Wen Ma, Peng Xiao, Yani Gu, Jie Pan, Xinyun Zhang, Chen Zhao, Yunli Yu. (2026) Moxifloxacin-Mediated Downregulation of Intestinal P-Glycoprotein Alters the Pharmacokinetics of Dabigatran Etexilate: Mechanistic Insights in Rats and PBPK Model-Informed Dose Optimization. Pharmaceutics, 18 (8):(1031). [PMID:][10.3390/pharmaceutics18081031]
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