Somatostatin - ≥95% , CAS No.51110-01-1

CAS: 51110-01-1 Cat. No.: S275022 Formula: C₇₆H₁₀₄N₁₈O₁₉S₂ Peso molecolare: 1637.89 PubChem CID: 16129681

GRADE & PURITY ≥95%

Synonyms

AGCKNFFFFWWKTFTSC (modifiche: ponte disolfuro tra 3 - 14) | AKOS015896026 | BCA11001 | SCHEMBL3046327 | SOMATOSTATINA | Stilamina | AGCKNFFFFWWKTFTSC | Somatostain Acetato | FT-0630640 | L000577 | Panhibin | Somatostatina 14 | NHXLMOGPVYXJNR-UHFFFAOYSA-N

Storage

Store at -20°C,Desiccated

Shipped In

Cassetta del ghiaccio + cuscini per il ghiaccio

Panoramica

H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (ponte disolfuro: Cys3-Cys14).
La somatostatina è un tetradecapeptide in grado di sopprimere la secrezione dell'ormone della crescita (GH) e di controllare la secrezione di ormoni ipofisari nel sistema nervoso centrale umano.

Specifications

Sinonimi

AGCKNFFFFWWKTFTSC (modifiche: ponte disolfuro tra 3 - 14) | AKOS015896026 | BCA11001 | SCHEMBL3046327 | SOMATOSTATINA | Stilamina | AGCKNFFFFWWKTFTSC | Somatostain Acetato | FT-0630640 | L000577 | Panhibin | Somatostatina 14 | NHXLMOGPVYXJNR-UHFFFAOYSA-N

Specifiche e purezza

≥95%

Condizioni di conservazione di stoccaggio

Store at -20°C,Desiccated

Spedito in

Cassetta del ghiaccio + cuscini per il ghiaccio

Purezza

≥95%

Nomi e identificatori

Pubchem Sid

488199048

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488199048

Sorrisi canonici

CC(C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)CC5=CC=CC=C5)CC(=O)N)CCCCN)NC(=O)CNC(=O)C(C)N)C(=O)O)CO)C(C)O)CC6=CC=CC=C6)O

IUPAC Name

19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-37-[[2-(2-aminopropanoylamino)acetyl]amino]-13,25,28-tribenzyl-10,16-bis(1-hydroxyethyl)-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecazacyclooctatriacontane-4-carboxylic acid

InChIKey

NHXLMOGPVYXJNR-UHFFFAOYSA-N

INCHI

1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)

Isomeri SMILES

CC(C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)CC5=CC=CC=C5)CC(=O)N)CCCCN)NC(=O)CNC(=O)C(C)N)C(=O)O)CO)C(C)O)CC6=CC=CC=C6)O

PubChem CID

16129681

Peso molecolare

1637.89

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic Polymers
    • Classe Polypeptides

• Kingdom: Organic compounds
• Superclass: Organic Polymers
• Classe: Polypeptides
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Polypeptides
• Alternative Parents: Cyclic peptides Macrolactams N-acyl-alpha amino acids and derivatives Alpha amino acid amides Alanine and derivatives 3-alkylindoles Substituted pyrroles Benzene and substituted derivatives Heteroaromatic compounds Primary carboxylic acid amides Organic disulfides Secondary alcohols Amino acids Secondary carboxylic acid amides Lactams Monocarboxylic acids and derivatives Azacyclic compounds Carboxylic acids Carbonyl compounds Hydrocarbon derivatives Monoalkylamines Organic oxides Organopnictogen compounds Primary alcohols
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Polypeptide - Cyclic alpha peptide - N-acyl-alpha amino acid or derivatives - Macrolactam - Alpha-amino acid amide - Alanine or derivatives - N-substituted-alpha-amino acid - Alpha-amino acid or derivatives - 3-alkylindole - Indole or derivatives - Indole - Monocyclic benzene moiety - Benzenoid - Substituted pyrrole - Heteroaromatic compound - Pyrrole - Secondary alcohol - Primary carboxylic acid amide - Secondary carboxylic acid amide - Carboxamide group - Lactam - Amino acid - Organic disulfide - Amino acid or derivatives - Azacycle - Carboxylic acid derivative - Carboxylic acid - Organoheterocyclic compound - Monocarboxylic acid or derivatives - Primary amine - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Alcohol - Carbonyl group - Hydrocarbon derivative - Organic oxide - Primary alcohol - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Amine - Aromatic heteropolycyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as polypeptides. These are peptides containing ten or more amino acid residues.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Obiettivi associati (umani)

SST Tbio Somatostatin (0 Activities)

Discover Target: SST

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Proprietà chimiche e fisiche

• Solubilità: Soluble in water
• Peso molecolare: 1637.900 g/mol
• XLogP3: -3.100
• Hydrogen Bond Donor Count: 22
• Hydrogen Bond Acceptor Count: 24
• Rotatable Bond Count: 26
• Exact Mass: 1636.72 Da
• Monoisotopic Mass: 1636.72 Da
• Topological Polar Surface Area: 664.000 Ų
• Heavy Atom Count: 115
• Formal Charge: 0
• Complexity: 3240.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 15
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1