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Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 19 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
Sparfloxacin (AT-4140, CI-978, PD 131501) is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity.
In vitro
In vivo
Sparfloxacin showed good oral efficacy against systemic infections with Staphylococcus aureus , Streptococcus pyogenes , Streptococcus pneumoniae , Escherichia coli , and Pseudomonas aeruginosa in mice.
Cell Data
cell lines:
Concentrations:
Incubation Time:
Powder Purity:≥99%
| ALogP | 0.1 |
|---|
| Isomeri SMILES | C[C@@H]1CN(C[C@@H](N1)C)C2=C(C(=C3C(=C2F)N(C=C(C3=O)C(=O)O)C4CC4)N)F |
|---|---|
| WGK Germania | 2 |
| RTECS | VB1986500 |
| PubChem CID | 60464 |
| Peso molecolare | 392.4 |
| Beilstein | 9170271 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Punto di infiammabilità (°F) | 230°F |
|---|---|
| Punto di infiammabilità (°C) | >110°C |
| Punto di ebollizione (°C) | 640℃ |
| Punto di fusione (°C) | 265°C |
| 1. Wang Jiarui, Feng Juanjuan, Sun Min, Lian Yujing, Wang Minglin, Qiao Luqin. (2022) Sulfonic acid-functionalized covalent organic frameworks as the coating for stir bar sorptive extraction of fluoroquinolones in milk samples. MICROCHIMICA ACTA, 190 (1): (1-9). [PMID:36469152] [10.1007/s00604-022-05534-9] |
| 2. Jia-Yu Zeng, Yu-Qi Liang, Yan-Ni Wu, Xiao-Yi Wu, Jia-Ping Lai, Hui Sun. (2022) Synthesis and application of novel N, Si-carbon dots for the ratiometric fluorescent monitoring of the antibiotic balofloxacin in tablets and serum. RSC Advances, 12 (45): (29585-29594). [PMID:36320748] [10.1039/D2RA02932D] |
| 3. Zhenyu Lu, Gongke Li, Yufei Hu. (2022) A Tb3+ functionalized triazine-porous organic framework as a ratiometric fluorescent sensor for determination of ciprofloxacin in aquatic products. NEW JOURNAL OF CHEMISTRY, 46 (40): (19153-19160). [PMID:] [10.1039/D2NJ03657F] |
| 4. Jin'ai Chen, Yuting Jin, Taotao Ren, Shuo Wang, Xianghong Wang, Fuyuan Zhang, Yiwei Tang. (2022) A novel terbium (III) and aptamer-based probe for label-free detection of three fluoroquinolones in honey and water samples. FOOD CHEMISTRY, [PMID:35334319] [10.1016/j.foodchem.2022.132751] |
| 5. Liang Yu-Qi, Wu Xiao-Yi, Zeng Jia-Yu, Wu Yan-Ni, Lai Jia-Ping, Sun Hui. (2022) A novel fluorescence ratio probe based on dual-emission carbon dots for highly selective and sensitive detection of chlortetracycline and cell imaging. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 414 (9): (3043-3055). [PMID:35195741] [10.1007/s00216-022-03908-9] |
| 6. Jin Yuting, Yan Rongfang, Wang Shuo, Wang Xianghong, Zhang Xuemei, Tang Yiwei. (2022) Dipeptide nanoparticle and aptamer-based hybrid fluorescence platform for enrofloxacin determination. MICROCHIMICA ACTA, 189 (3): (1-8). [PMID:35147788] [10.1007/s00604-022-05182-z] |
| 7. Xiaojun Dai, Yanfei Wu, Zhuanhong Jia, Chunmiao Bo. (2021) Preparation of water-compatible magnetic imprinted nanospheres using heptakis (β-cyclodextrin-ionic liquid) as functional monomer for selective recognition of fluoroquinolones in water samples. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2021.106793] |
| 8. Qi Xue, Cong Wang, Yao Lin, Ting-Fu Jiang, Zhihua Lv. (2021) Determination of fluoroquinolones illegally added in traditional prostate medicines by ultrasonic-assisted dispersive liquid liquid micro-extraction based on deep eutectic solvent combined with quantitative 19F nuclear magnetic resonance method. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2021.106725] |
| 9. Gongxi Qiao, Gui Chen, Qin Wen, Wanqiang Liu, Jinwei Gao, Zhiqiang Yu, Qianming Wang. (2020) Rapid conversion from common precursors to carbon dots in large scale: Spectral controls, optical sensing, cellular imaging and LEDs application. JOURNAL OF COLLOID AND INTERFACE SCIENCE, [PMID:32682119] [10.1016/j.jcis.2020.07.034] |
| 10. Kaili Yu, Mei-E. Yue, Jie Xu, Ting-Fu Jiang. (2020) Determination of fluoroquinolones in milk, honey and water samples by salting out-assisted dispersive liquid-liquid microextraction based on deep eutectic solvent combined with MECC. FOOD CHEMISTRY, [PMID:32622188] [10.1016/j.foodchem.2020.127371] |
| 11. Shuai Han, Liang Yang, Zhigang Wen, Suyun Chu, Mei Wang, Zhenyang Wang, Changlong Jiang. (2020) A dual-response ratiometric fluorescent sensor by europium-doped CdTe quantum dots for visual and colorimetric detection of tetracycline. JOURNAL OF HAZARDOUS MATERIALS, [PMID:32768819] [10.1016/j.jhazmat.2020.122894] |
| 12. Zhi Shen, Cheng Zhang, Xinling Yu, Jian Li, Zhenyang Wang, Zhongping Zhang, Bianhua Liu. (2018) Microwave-assisted synthesis of cyclen functional carbon dots to construct a ratiometric fluorescent probe for tetracycline detection. Journal of Materials Chemistry C, 6 (36): (9636-9641). [PMID:] [10.1039/C8TC02982B] |
| 13. Suyu Ren, Jing Tao, Feng Tan, Ying Cui, Xiaona Li, Jingwen Chen, Xin He, Yi Wang. (2018) Diffusive gradients in thin films based on MOF-derived porous carbon binding gel for in-situ measurement of antibiotics in waters. SCIENCE OF THE TOTAL ENVIRONMENT, [PMID:30029123] [10.1016/j.scitotenv.2018.07.013] |
| 14. Wang Nan, Wang Yan-Fei, Omer Ahmed M., Ouyang Xiao-kun. (2017) Fabrication of novel surface-imprinted magnetic graphene oxide-grafted cellulose nanocrystals for selective extraction and fast adsorption of fluoroquinolones from water. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 409 (28): (6643-6653). [PMID:28940000] [10.1007/s00216-017-0619-9] |
| 15. Yan-Fei Wang, Yang-Guang Wang, Xiao-Kun Ouyang, Li-Ye Yang. (2017) Surface-Imprinted Magnetic Carboxylated Cellulose Nanocrystals for the Highly Selective Extraction of Six Fluoroquinolones from Egg Samples. ACS Applied Materials & Interfaces, [PMID:28005332] [10.1021/acsami.6b12206] |
| 16. Ruijie Tang, Lingfei Li, Yaowei Zhu, Minghui Zhan, Jun Zhao, Changlong Jiang, Bianhua Liu. (2025) Ratiometric fluorescent sensor for sensitive visualization of full-spectrum fluoroquinolone antibiotic residues in the environment. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2025.113260] |
| 17. Tianci Lv, Fubin Liu, Mengqian Xiao, Ying Liu, Litao Wang, Guihua Gao. (2024) Synthesis of reusable hierarchical Pore PVDF-MIL-101(Cr) foam for Solid phase extraction of fluoroquinolones from water and its adsorption behavior for anionic and cationic dyes. JOURNAL OF CHROMATOGRAPHY A, [PMID:39637615] [10.1016/j.chroma.2024.465577] |
| 18. Huang Xiao-Qing, Wang Mao-Yu, Wang Xiao-Chen, Shi Xin, Li Rui-Wen, Wu Shuang, Li Ying. (2025) A surface-imprinting lanthanide fluorescent hybrid probe on SiO2 microspheres for the detection of enrofloxacin. MICROCHIMICA ACTA, 192 (8): (1-12). [PMID:40731103] [10.1007/s00604-025-07369-6] |
| 19. Zhiwen Li, Jiyue Zhang, Qiyao Sun, Wenwen Shi, Tingxian Tao, Yingqiang Fu. (2022) Moxifloxacin detection based on fluorescence resonance energy transfer from carbon quantum dots to moxifloxacin using a ratiometric fluorescence probe. NEW JOURNAL OF CHEMISTRY, 46 (9): (4226-4232). [PMID:] [10.1039/D1NJ05961K] |
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