(+)-Sparteine - Moligand™, ≥98% , CAS No.492-08-0

CAS: 492-08-0 Cat. No.: S121165 Molecular Weight: 234.39 EC Number: 805-899-0 PubChem CID: 7014

GRADE & PURITY Moligand™, ≥98%

Synonyms

IDI1_000631 | Q66604441 | 7,14-Methano-2H,6H-dipyrido(1,2-a:1',2'-e)(1,5)diazocine, decahydro-, (7R,7aR,14R,14aS)- | Tocosamine (Sulfate pentahydrate) | (1R,2S,9R,10R)-7,15-diazatetracyclo[7.7.1.02,7.010,15]heptadecane | HY-W008350 | NSC376144 | DivK1c_00

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Overview

(+)-Sparteine is a natural alkaloid acting as a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons.

Specifications

Synonyms

IDI1_000631 | Q66604441 | 7, 14-Methano-2H, 6H-dipyrido(1, 2-a:1', 2'-e)(1, 5)diazocine, decahydro-, (7R, 7aR, 14R, 14aS)- | Tocosamine (Sulfate pentahydrate) | (1R, 2S, 9R, 10R)-7, 15-diazatetracyclo[7.7.1.02, 7.010, 15]heptadecane | HY-W008350 | NSC376144 | DivK1c_00

Specifications & Purity

Moligand™, ≥98%

Storage

Protected from light, Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

INHIBITOR

Purity

≥98%

Names and Identifiers

• Pubchem Sid: 504751225
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504751225
• Canonical Smiles: C1CCN2CC3CC(C2C1)CN4C3CCCC4
• IUPAC Name: (1R,2S,9R,10R)-7,15-diazatetracyclo[7.7.1.02,7.010,15]heptadecane
• InChIKey: SLRCCWJSBJZJBV-TUVASFSCSA-N
• INCHI: 1S/C15H26N2/c1-3-7-16-11-13-9-12(14(16)5-1)10-17-8-4-2-6-15(13)17/h12-15H,1-11H2/t12-,13-,14-,15+/m1/s1
• Isomeric SMILES: C1CCN2C[C@H]3C[C@@H]([C@H]2C1)CN4[C@H]3CCCC4
• RTECS: RT0620000
• PubChem CID: 7014
• Molecular Weight: 234.39
• Reaxy-Rn: 82448

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Alkaloids and derivatives
    • Class Lupin alkaloids
      • Subclass Sparteine, lupanine, and related alkaloids

• Kingdom: Organic compounds
• Superclass: Alkaloids and derivatives
• Class: Lupin alkaloids
• Subclass: Sparteine, lupanine, and related alkaloids
• Intermediate Tree Nodes: Not available
• Direct Parent: Sparteine, lupanine, and related alkaloids
• Alternative Parents: Quinolizidines Piperidines Trialkylamines Azacyclic compounds Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aliphatic heteropolycyclic compounds
• Substituents: Sparteine-lupanine skeleton - Quinolizidine - Piperidine - Tertiary aliphatic amine - Tertiary amine - Azacycle - Organoheterocyclic compound - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Amine - Aliphatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as sparteine, lupanine, and related alkaloids. These are alkaloids with a structure based on either sparteine, lupanine, or derivatives thereof. These are tetracyclic compounds made of two fused quinolizidine ring systems.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: H2O : 2.86 mg/mL (12.20 mM; Need ultrasonic)
• Sensitivity: light and moisture and air and heat sensitive
• Refractive Index: 1.53
• Specific Rotation[α]: +18° (C=1,EtOH)
• Flash Point(°C): 148 °C
• Boil Point(°C): 174°C/8mmHg
• Molecular Weight: 234.380 g/mol
• XLogP3: 2.500
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 234.21 Da
• Monoisotopic Mass: 234.21 Da
• Topological Polar Surface Area: 6.500 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 263.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Hongzhu Lai, Li Jiang, Wenyan Huang, Bibiao Jiang, Daoyong Chen.  (2025)  Synthesis and Directed One-Dimensional Self-Assembly of Dumbbell-Shaped Single-Chain Particles.  JOURNAL OF POLYMER SCIENCE,  63  (8): (1938-1946).  [PMID:] [10.1002/pol.20250020]