SR 19881 - ≥98% , CAS No.2213490-89-0

CAS: 2213490-89-0 Cat. No.: S412437 Molecular Weight: 312.41 PubChem CID: 145978085

GRADE & PURITY ≥98%

Storage

Store at 2-8°C

Shipped In

Wet ice

Overview

Information

SR 19881 is a potent full agonist of ERRγ with EC50 of 0.39 μM and 4.7 μM in a binding assay and a cell-based assay, respectively. SR 19881 is also equipotent on ERRβ with EC50 of 0.63 μM making it an equipotent dual agonist of ERRβ/γ.

Specifications

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

SR 19881 is a potent full agonist of ERRγ with EC50 of 0.39 μM and 4.7 μM in a binding assay and a cell-based assay, respectively. SR 19881 is also equipotent on ERRβ with EC50 of 0.63 μM making it an equipotent dual agonist of ERRβ/γ.

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Names and Identifiers

• Canonical Smiles: CCN(CC)C1=CC=C(C=C1)CCNC(=O)C2=CC=C(C=C2)O
• IUPAC Name: N-[2-[4-(diethylamino)phenyl]ethyl]-4-hydroxybenzamide
• InChIKey: BECNZUWIKCKMJG-UHFFFAOYSA-N
• INCHI: 1S/C19H24N2O2/c1-3-21(4-2)17-9-5-15(6-10-17)13-14-20-19(23)16-7-11-18(22)12-8-16/h5-12,22H,3-4,13-14H2,1-2H3,(H,20,23)
• Isomeric SMILES: CCN(CC)C1=CC=C(C=C1)CCNC(=O)C2=CC=C(C=C2)O
• PubChem CID: 145978085
• Molecular Weight: 312.41

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Benzene and substituted derivatives
      • Subclass Benzoic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Benzene and substituted derivatives
• Subclass: Benzoic acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Benzamides
• Alternative Parents: Dialkylarylamines Benzoyl derivatives Aniline and substituted anilines 1-hydroxy-2-unsubstituted benzenoids Secondary carboxylic acid amides Amino acids and derivatives Organopnictogen compounds Organooxygen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Benzamide - Aniline or substituted anilines - Dialkylarylamine - Tertiary aliphatic/aromatic amine - Benzoyl - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Tertiary amine - Secondary carboxylic acid amide - Carboxamide group - Amino acid or derivatives - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Amine - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as benzamides. These are organic compounds containing a carboxamido substituent attached to a benzene ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

ESRRA Tchem Estrogen-related receptor alpha (573 Activities)

Discover Target: ESRRA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ESRRB Tchem Estrogen-related receptor beta (173 Activities)

Discover Target: ESRRB

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ESRRG Tchem Estrogen-related receptor gamma (587 Activities)

Discover Target: ESRRG

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action