10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
SR-4370 is a potent and selective inhibitor of class I HDACs with IC50 of 0.13 µM, 0.58 µM, 0.006 µM, 2.3 µM, 3.7 µM forHDAC 1,HDAC 2,HDAC 3,HDAC 8,HDAC 6, respectively.SR-4370 suppresses AR signaling and in vivo prostate tumor growth.
Targets
HDAC3 (Cell-free assay); HDAC1 (Cell-free assay); HDAC2 (Cell-free assay); HDAC8 (Cell-free assay); HDAC6 (Cell-free assay) ;0.006 μM; 0.13 μM; 0.58 μM; 2.3 μM; 3.7 μM
In vitro
SR-4370 can induce cell death of the aggressive breast cancer MDAMB-231 cells with IC50 of 12.6 μM..
Cell Research(from reference)
Cell lines：MDA-MB-231 cells
Concentrations：0-100 μM
| ALogP | 3.804 |
|---|---|
| Conteggio HBD | 2 |
| Legame rotabile | 6 |
| Pubchem Sid | 528767182 |
|---|---|
| Sorrisi canonici | CCCCNNC(=O)C1=CC=C(C=C1)C2=C(C(=CC=C2)F)F |
| IUPAC Name | N'-butyl-4-(2,3-difluorophenyl)benzohydrazide |
| InChIKey | OSQKWTZHYXRTBG-UHFFFAOYSA-N |
| INCHI | 1S/C17H18F2N2O/c1-2-3-11-20-21-17(22)13-9-7-12(8-10-13)14-5-4-6-15(18)16(14)19/h4-10,20H,2-3,11H2,1H3,(H,21,22) |
| Isomeri SMILES | CCCCNNC(=O)C1=CC=C(C=C1)C2=C(C(=CC=C2)F)F |
| PubChem CID | 118418385 |
| Peso molecolare | 304.33 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Classe | Benzene and substituted derivatives |
| Subclass | Benzoic acids and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Benzoic acids and derivatives |
| Alternative Parents | Benzoyl derivatives Fluorobenzenes Carboxylic acids and derivatives Organopnictogen compounds Organooxygen compounds Organonitrogen compounds Organofluorides Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Benzoic acid or derivatives - Benzoyl - Halobenzene - Fluorobenzene - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Aromatic homomonocyclic compound |
| Descrizione | This compound belongs to the class of organic compounds known as benzoic acids and derivatives. These are organic compounds containing a carboxylic acid substituent attached to a benzene ring. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Data | Oggetto |
|---|---|---|---|
 F2419032 | Certificate of Analysis | May 13, 2026 | S422227 |
| DMSO (mg/mL) Solubilità massima | 61 |
|---|---|
| DMSO (mM) Solubilità massima | 200.44031150396 |
| Acqua (mg/mL) Solubilità massima | ＜1 |
| Peso molecolare | 304.330 g/mol |
| XLogP3 | 4.000 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 6 |
| Exact Mass | 304.139 Da |
| Monoisotopic Mass | 304.139 Da |
| Topological Polar Surface Area | 41.100 Ų |
| Heavy Atom Count | 22 |
| Formal Charge | 0 |
| Complexity | 346.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
